PMID- 22432552 OWN - NLM STAT- MEDLINE DCOM- 20120731 LR - 20220408 IS - 1751-7133 (Electronic) IS - 1527-5299 (Linking) VI - 18 IP - 2 DP - 2012 Mar-Apr TI - Adherence to evidence-based guidelines for heart failure in physicians and their patients: lessons from the Heart Failure Adherence Retention Trial (HART). PG - 73-8 LID - 10.1111/j.1751-7133.2011.00263.x [doi] AB - The Heart Failure Adherence and Retention Trial (HART) provided an opportunity to determine adherence to evidence-based guidelines (EBG) in patients with heart failure (HF). Ten hospitals were the source of 692 patients with HF (EF < 40%). Physicians of patients with HF were classified as adherent to EBG if the patient chart audit showed they were on a beta-blocker, ACE-inhibitor (ACE-I), or angiotensin receptor blocker (ARB). Patients were classified as adherent to EBG if MEMS pill caps were used appropriately more than 80% of the time. Sixty-three percent of physicians prescribed evidence-based medications that were adherent to clinical practice guidelines. New York Heart Association (NYHA) III patients were less likely to be adherent (P < 0.001), as were those with renal disease (P < 0.001) and asthmatics (P < 0.001). Nonadherent physicians were less likely to treat patients with beta-blockers (39% vs 98%, P < 0.001) and ACE-I or ARBs (71% vs 98% P < 0.001). Thirty-seven percent of patients prescribed evidence-based therapy failed to use the MEMS pill cap bottles appropriately and were more likely a minority or higher NYHA class. Adherence to evidence-based therapy is less than optimal in HF patients based on a combination of both physician and patient nonadherence. CI - (c) 2011 Wiley Periodicals, Inc. FAU - Calvin, James E AU - Calvin JE AD - Section of Cardiology, Rush University Medical Center, Chicago, IL 60612-3833, USA. james_calvin@rush.edu FAU - Shanbhag, Sujata AU - Shanbhag S FAU - Avery, Elizabeth AU - Avery E FAU - Kane, John AU - Kane J FAU - Richardson, Dejuran AU - Richardson D FAU - Powell, Lynda AU - Powell L LA - eng PT - Journal Article DEP - 20111103 PL - United States TA - Congest Heart Fail JT - Congestive heart failure (Greenwich, Conn.) JID - 9714174 RN - 0 (Adrenergic beta-Antagonists) RN - 0 (Angiotensin Receptor Antagonists) RN - 0 (Angiotensin-Converting Enzyme Inhibitors) SB - IM MH - Adrenergic beta-Antagonists/therapeutic use MH - Angiotensin Receptor Antagonists/therapeutic use MH - Angiotensin-Converting Enzyme Inhibitors/therapeutic use MH - Chi-Square Distribution MH - Chicago MH - Confidence Intervals MH - Evidence-Based Medicine/*methods MH - Female MH - *Guideline Adherence MH - Heart Failure/*drug therapy MH - Humans MH - Logistic Models MH - Male MH - Medication Adherence/*statistics & numerical data MH - Middle Aged MH - Odds Ratio MH - Patient Compliance MH - Patient Education as Topic MH - *Practice Guidelines as Topic MH - Practice Patterns, Physicians'/*statistics & numerical data EDAT- 2012/03/22 06:00 MHDA- 2012/08/01 06:00 CRDT- 2012/03/22 06:00 PHST- 2012/03/22 06:00 [entrez] PHST- 2012/03/22 06:00 [pubmed] PHST- 2012/08/01 06:00 [medline] AID - 10.1111/j.1751-7133.2011.00263.x [doi] PST - ppublish SO - Congest Heart Fail. 2012 Mar-Apr;18(2):73-8. doi: 10.1111/j.1751-7133.2011.00263.x. Epub 2011 Nov 3.