PMID- 22433795
OWN - NLM
STAT- MEDLINE
DCOM- 20120719
LR  - 20120508
IS  - 1473-5687 (Electronic)
IS  - 0954-691X (Linking)
VI  - 24
IP  - 6
DP  - 2012 Jun
TI  - Eosinophilic gastroenteritis associated with multiple gastric cancer.
PG  - 727-30
LID - 10.1097/MEG.0b013e32835272ea [doi]
AB  - Eosinophilic gastroenteritis (EG) is an inflammation of the digestive tract that 
      is characterized by eosinophilic infiltration. There are no specific symptoms, 
      and are related to the layer in which eosinophilic infiltration is observed. A 
      69-year-old Japanese man presented to our hospital with a history of general 
      malaise, diarrhea, and dysgeusia. Esophagogastroduodenoscopy showed reddish 
      elevated lesions that were edematous all over the gastric mucosa. In addition, 
      three tumors were also observed. The biopsies of the reddish elevated mucosa 
      revealed eosinophilic infiltration and tubular adenocarcinoma from the tumors. 
      Colonoscopy showed abnormal reddish elevated mucosa. The biopsies from the 
      reddish elevated mucosa showed eosinophilic infiltration. From the abdominal 
      contrast computed tomography scan, tumor stain was seen in the anterior wall of 
      the gastric body. No ascites, intestinal wall thickening, or lymph node swelling 
      were found. A slight elevation in the serum immunoglobulin E (IgE), 480 IU/ml, 
      was found from the laboratory test results; other laboratory results were within 
      normal limits including the number of peripheral eosinophils. No specific 
      allergen was found from the multiple antigen simultaneous test and from the skin 
      patch test. The parasitic immunodiagnosis was negative. He was diagnosed with EG 
      associated with gastric cancer and underwent total gastrectomy, regional lymph 
      node dissection with reconstruction by a Roux-en-Y method. He was prescribed 
      prednisolone after the operation and showed a good clinical response. There are 
      many case reports on EG, but none of them were associated with cancer. We 
      encountered a case of EG associated with multiple gastric cancer; the patient 
      underwent total gastrectomy.
FAU - Otowa, Yasunori
AU  - Otowa Y
AD  - Department of Surgery, National Hospital Organization Kobe Medical Center, Kobe, 
      Japan. otowa_y@kobemc.go.jp
FAU - Mitsutsuji, Masaaki
AU  - Mitsutsuji M
FAU - Urade, Takeshi
AU  - Urade T
FAU - Chono, Teruhiro
AU  - Chono T
FAU - Morimoto, Haruki
AU  - Morimoto H
FAU - Yokoyama, Kunio
AU  - Yokoyama K
FAU - Hirata, Kenro
AU  - Hirata K
FAU - Kawamura, Shiro
AU  - Kawamura S
FAU - Shimada, Etsuji
AU  - Shimada E
FAU - Fujita, Masayuki
AU  - Fujita M
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Eur J Gastroenterol Hepatol
JT  - European journal of gastroenterology & hepatology
JID - 9000874
RN  - Eosinophilic enteropathy
SB  - IM
MH  - Adenocarcinoma/*complications/diagnosis/surgery
MH  - Aged
MH  - Biopsy
MH  - Colon/pathology
MH  - Endoscopy, Gastrointestinal/methods
MH  - Enteritis/diagnosis/*etiology/pathology
MH  - Eosinophilia/diagnosis/*etiology/pathology
MH  - Gastrectomy
MH  - Gastritis/diagnosis/*etiology/pathology
MH  - Humans
MH  - Male
MH  - Stomach/pathology
MH  - Stomach Neoplasms/*complications/diagnosis/surgery
EDAT- 2012/03/22 06:00
MHDA- 2012/07/20 06:00
CRDT- 2012/03/22 06:00
PHST- 2012/03/22 06:00 [entrez]
PHST- 2012/03/22 06:00 [pubmed]
PHST- 2012/07/20 06:00 [medline]
AID - 10.1097/MEG.0b013e32835272ea [doi]
PST - ppublish
SO  - Eur J Gastroenterol Hepatol. 2012 Jun;24(6):727-30. doi: 
      10.1097/MEG.0b013e32835272ea.