PMID- 22440647
OWN - NLM
STAT- MEDLINE
DCOM- 20121105
LR  - 20120615
IS  - 1095-9572 (Electronic)
IS  - 1053-8119 (Linking)
VI  - 61
IP  - 4
DP  - 2012 Jul 16
TI  - Medial orbitofrontal cortex is associated with shifting decision thresholds in 
      self-serving cognition.
PG  - 889-98
LID - 10.1016/j.neuroimage.2012.03.011 [doi]
AB  - Recent research has begun to identify neural regions associated with self-serving 
      cognition, that is, the tendency to make claims that cast the self in an overly 
      flattering light, yet little is known about the mechanisms supported by neural 
      activation underlying self-serving cognition. One possibility suggested by 
      current research is that MOFC, a region that shows reduced recruitment in 
      relation to self-serving cognition, may support changes in the decision 
      thresholds that influence whether information should be expressed in an 
      evaluation. The current fMRI study addresses this question by combining a signal 
      detection approach and a contextual manipulation that permits the measurement of 
      changes in decision threshold. Participants evaluated their familiarity with 
      blocks of existent and nonexistent information when they believed that 
      self-serving claims of knowledge could either be exposed (accountable condition) 
      or not (unaccountable condition). When held accountable, participants tended to 
      shift their decision thresholds in a conservative (i.e., less self-serving) 
      direction and showed greater activation in orbitofrontal cortex (OFC), medial 
      prefrontal cortex (MPFC) and dorsal anterior cingulate cortex (dACC). 
      Furthermore, the extent to which participants adopted more conservative (i.e., 
      less self-serving) decision thresholds as a function of context (i.e., 
      accountability), the more they recruited MOFC activation. These findings refine 
      current knowledge about the mechanisms performed by neural regions involved in 
      self-serving cognition and suggest a role for MOFC in changing decision 
      thresholds that influence whether information should be expressed in an 
      evaluation.
CI  - Copyright (c) 2012 Elsevier Inc. All rights reserved.
FAU - Hughes, Brent L
AU  - Hughes BL
AD  - Department of Psychology and Imaging Research Center, The University of Texas at 
      Austin, Austin, TX 78712, USA.
FAU - Beer, Jennifer S
AU  - Beer JS
LA  - eng
PT  - Journal Article
DEP - 20120313
PL  - United States
TA  - Neuroimage
JT  - NeuroImage
JID - 9215515
SB  - IM
MH  - *Brain Mapping
MH  - Cognition/*physiology
MH  - Female
MH  - Frontal Lobe/*physiology
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - *Self Concept
MH  - Young Adult
EDAT- 2012/03/24 06:00
MHDA- 2012/11/06 06:00
CRDT- 2012/03/24 06:00
PHST- 2011/11/23 00:00 [received]
PHST- 2012/02/06 00:00 [revised]
PHST- 2012/03/05 00:00 [accepted]
PHST- 2012/03/24 06:00 [entrez]
PHST- 2012/03/24 06:00 [pubmed]
PHST- 2012/11/06 06:00 [medline]
AID - S1053-8119(12)00283-2 [pii]
AID - 10.1016/j.neuroimage.2012.03.011 [doi]
PST - ppublish
SO  - Neuroimage. 2012 Jul 16;61(4):889-98. doi: 10.1016/j.neuroimage.2012.03.011. Epub 
      2012 Mar 13.