PMID- 22444338
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20120326
IS  - 1751-7311 (Print)
IS  - 1751-7311 (Linking)
VI  - 1
IP  - 3
DP  - 2007 Mar
TI  - Expression of retinoid receptors during rabbit lung development.
PG  - 403-9
LID - 10.1017/S1751731107705335 [doi]
AB  - Rabbit lung is often used to study the pathophysiology of some congenital 
      anomalies affecting the lung because its development is very comparable with that 
      of human. Retinoids and the molecular transducers of the retinoic signal play a 
      crucial role in mammalian lung development. In the rabbit, the molecular retinoic 
      pathway has so far been poorly studied. As a first step in elucidating this 
      process, we aimed to identify the retinoic acid receptors (RARs) and retinoid X 
      receptors (RXRs). We cloned a part of the nuclear receptors (RARs and RXRs), and 
      we used reverse transcription - polymerase chain reaction (RT-PCR) and 
      immunohistochemistry assays to demonstrate the presence of RAR (alpha,beta) and RXR (alpha, 
      beta) at all stages of rabbit lung development. Our results initiate further 
      analysis into the molecular and genetic functions of retinoids during normal and 
      pathological rabbit lung development including the surgical model of congenital 
      diaphragmatic hernia.
FAU - Coste, K
AU  - Coste K
AD  - Universite d'Auvergne, JE2447 ARDEMO, F-63000, Clermont-Ferrand, France.
FAU - Gallot, D
AU  - Gallot D
FAU - Marceau, G
AU  - Marceau G
FAU - Jani, J
AU  - Jani J
FAU - Deprest, J
AU  - Deprest J
FAU - Labbe, A
AU  - Labbe A
FAU - Lemery, D
AU  - Lemery D
FAU - Sapin, V
AU  - Sapin V
LA  - eng
PT  - Journal Article
PL  - England
TA  - Animal
JT  - Animal : an international journal of animal bioscience
JID - 101303270
EDAT- 2007/03/01 00:00
MHDA- 2007/03/01 00:01
CRDT- 2012/03/27 06:00
PHST- 2012/03/27 06:00 [entrez]
PHST- 2007/03/01 00:00 [pubmed]
PHST- 2007/03/01 00:01 [medline]
AID - S1751731107705335 [pii]
AID - 10.1017/S1751731107705335 [doi]
PST - ppublish
SO  - Animal. 2007 Mar;1(3):403-9. doi: 10.1017/S1751731107705335.