PMID- 22450615
OWN - NLM
STAT- MEDLINE
DCOM- 20120808
LR  - 20211021
IS  - 1545-7222 (Electronic)
IS  - 0895-0172 (Print)
IS  - 0895-0172 (Linking)
VI  - 24
IP  - 1
DP  - 2012 Winter
TI  - Sustained attention deficits among HIV-positive individuals with comorbid bipolar 
      disorder.
PG  - 61-70
LID - 10.1176/appi.neuropsych.11010028 [doi]
AB  - Difficulties with sustained attention have been found among both persons with HIV 
      infection (HIV+) and bipolar disorder (BD). The authors examined sustained 
      attention among 39 HIV+ individuals with BD (HIV+/BD+) and 33 HIV-infected 
      individuals without BD (HIV+/BD-), using the Conners' Continuous Performance 
      Test-II (CPT-II). A Global Assessment of Functioning (GAF) score was also 
      assigned to each participant as an overall indicator of daily functioning 
      abilities. HIV+/BD+ participants had significantly worse performance on CPT-II 
      omission errors, hit reaction time SE (Hit RT SE), variability of SE, and 
      perseverations than HIV+/BD- participants. When examining CPT-II performance over 
      the six study blocks, both HIV+/BD+ and HIV+/BD- participants evidenced worse 
      performance on scores of commission errors and reaction times as the test 
      progressed. The authors also examined the effect of current mood state (i.e., 
      manic, depressive, euthymic) on CPT-II performance, but no significant 
      differences were observed across the various mood states. HIV+/BD+ participants 
      had significantly worse GAF scores than HIV+/BD- participants, which indicates 
      poorer overall functioning in the dually-affected group; among HIV+/BD+ persons, 
      significant negative correlations were found between GAF scores and CPT-II 
      omission and commission errors, detectability, and perseverations, indicating a 
      possible relationship between decrements in sustained attention and worse 
      daily-functioning outcomes.
FAU - Posada, Carolina
AU  - Posada C
AD  - San Diego State University/University of California, San Diego Joint Doctoral 
      Program in Clinical Psychology, San Diego, CA, USA.
FAU - Moore, David J
AU  - Moore DJ
FAU - Deutsch, Reena
AU  - Deutsch R
FAU - Rooney, Alexandra
AU  - Rooney A
FAU - Gouaux, Ben
AU  - Gouaux B
FAU - Letendre, Scott
AU  - Letendre S
FAU - Grant, Igor
AU  - Grant I
FAU - Atkinson, J Hampton
AU  - Atkinson JH
CN  - HIV Neurobehavioral Research Program Hnrp Group
LA  - eng
GR  - P30 MH062512/MH/NIMH NIH HHS/United States
GR  - R03 MH078785/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Neuropsychiatry Clin Neurosci
JT  - The Journal of neuropsychiatry and clinical neurosciences
JID - 8911344
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Attention Deficit Disorder with Hyperactivity/*etiology
MH  - Bipolar Disorder/*complications/*epidemiology
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Female
MH  - HIV Infections/*complications/diagnosis/*epidemiology
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neuropsychological Tests
MH  - Psychiatric Status Rating Scales
MH  - Psychomotor Performance
MH  - Severity of Illness Index
PMC - PMC3575087
MID - NIHMS439068
FIR - Grant, Igor
IR  - Grant I
FIR - Atkinson, J Hampton
IR  - Atkinson JH
FIR - Ellis, Ronald J
IR  - Ellis RJ
FIR - McCutchan, J Allen
IR  - McCutchan J
FIR - Marcotte, Thomas D
IR  - Marcotte TD
FIR - Marquie-Beck, Jennifer
IR  - Marquie-Beck J
FIR - Sherman, Melanie
IR  - Sherman M
FIR - Ellis, Ronald J
IR  - Ellis RJ
FIR - McCutchan, J Allen
IR  - McCutchan J
FIR - Letendre, Scott
IR  - Letendre S
FIR - Capparelli, Edmund
IR  - Capparelli E
FIR - Alexander, Terry
IR  - Alexander T
FIR - Rosario, Debra
IR  - Rosario D
FIR - LeBlanc, Shannon
IR  - LeBlanc S
FIR - Heaton, Robert K
IR  - Heaton RK
FIR - Woods, Steven Paul
IR  - Woods SP
FIR - Cherner, Mariana
IR  - Cherner M
FIR - Moore, David J
IR  - Moore DJ
FIR - Dawson, Matthew
IR  - Dawson M
FIR - Jernigan, Terry
IR  - Jernigan T
FIR - Fennema-Notestine, Christine
IR  - Fennema-Notestine C
FIR - Archibald, Sarah L
IR  - Archibald SL
FIR - Hesselink, John
IR  - Hesselink J
FIR - Annese, Jacopo
IR  - Annese J
FIR - Taylor, Michael J
IR  - Taylor MJ
FIR - Masliah, Eliezer
IR  - Masliah E
FIR - Everall, Ian
IR  - Everall I
FIR - Richman, Douglas
IR  - Richman D
FIR - Smith, David M
IR  - Smith DM
FIR - McCutchan, J Allen
IR  - McCutchan J
FIR - Achim, Cristian
IR  - Achim C
FIR - Lipton, Stuart
IR  - Lipton S
FIR - Atkinson, J Hampton
IR  - Atkinson J
FIR - von Jaeger, Rodney
IR  - von Jaeger R
FIR - Gamst, Anthony C
IR  - Gamst AC
FIR - Cushman, Clint
IR  - Cushman C
FIR - Abramson, Ian
IR  - Abramson I
FIR - Vaida, Florin
IR  - Vaida F
FIR - Deutsch, Reena
IR  - Deutsch R
FIR - Umlauf, Anya
IR  - Umlauf A
FIR - Wolfson, Tanya
IR  - Wolfson T
EDAT- 2012/03/28 06:00
MHDA- 2012/08/09 06:00
PMCR- 2013/02/18
CRDT- 2012/03/28 06:00
PHST- 2012/03/28 06:00 [entrez]
PHST- 2012/03/28 06:00 [pubmed]
PHST- 2012/08/09 06:00 [medline]
PHST- 2013/02/18 00:00 [pmc-release]
AID - 10.1176/appi.neuropsych.11010028 [doi]
PST - ppublish
SO  - J Neuropsychiatry Clin Neurosci. 2012 Winter;24(1):61-70. doi: 
      10.1176/appi.neuropsych.11010028.