PMID- 22452295 OWN - NLM STAT- MEDLINE DCOM- 20120809 LR - 20120426 IS - 1748-295X (Electronic) IS - 1748-2941 (Linking) VI - 14 IP - 2 DP - 2012 Jun TI - Clinical epidemiology, management and outcome of acute coronary syndromes in the Italian network on acute coronary syndromes (IN-ACS Outcome study). PG - 71-80 LID - 10.3109/17482941.2012.655296 [doi] AB - BACKGROUND: The Italian network on acute coronary syndromes outcome (IN-ACS Outcome) study is a nationwide observational, multicenter study with the aim to describe clinical epidemiology, management, 30-days and one-year outcomes of ACS in Italy. METHODS: All consecutive patients admitted for ACS to 38 hospitals, between December 2005 and February 2007, were enrolled in the study. Patient in-hospital details and follow-up data at 30-days and one-year were collected using a web-based CRF and stored in a central database. RESULTS: A total of 6045 patients (age 68 +/- 13 years) were enrolled: 2313 patients (38.3%) had ST elevation myocardial infarction (STEMI) and 3732 (61.7%) patients had NSTE-ACS. Primary PCI was performed in 1085 (46.9%) STEMI patients, thrombolysis in 590 (25.5%) patients, whereas 638 (27.6%) patients were not reperfused. Among patients with NSTE-ACS, coronary angiography was performed in 2797 (75%) patients, PCI in 1797 (48.2%) patients and CABG in 213 (5.7%) patients. Thirty-days and one-year mortality rates were 5.8% and 9.8%, in STEMI patients and 3.1% and 8.6%, in NSTE-ACS patients. CONCLUSIONS: The IN-ACS Outcome study showed that the management of ACS is still suboptimal. Although 30-days mortality is low, the one-year mortality is still substantial. FAU - Rizzello, Vittoria AU - Rizzello V AD - San Giovanni-Addolorata Hospital, Department of Cardiology, Rome, Italy. centrostudi@anmco.it FAU - Lucci, Donata AU - Lucci D FAU - Maggioni, Aldo P AU - Maggioni AP FAU - Giampaoli, Simona AU - Giampaoli S FAU - Greco, Cesare AU - Greco C FAU - Di Pasquale, Giuseppe AU - Di Pasquale G FAU - Pallotti, Maria Giovanna AU - Pallotti MG FAU - Mureddu, Gian Francesco AU - Mureddu GF FAU - Di Chiara, Antonio AU - Di Chiara A FAU - Boccanelli, Alessandro AU - Boccanelli A CN - IN-ACS Outcome Investigators LA - eng PT - Journal Article PT - Multicenter Study PT - Research Support, Non-U.S. Gov't DEP - 20120327 PL - England TA - Acute Card Care JT - Acute cardiac care JID - 101276603 SB - IM MH - Acute Coronary Syndrome/diagnosis/*mortality/therapy MH - Aged MH - Aged, 80 and over MH - Analysis of Variance MH - Angioplasty, Balloon, Coronary MH - Coronary Artery Bypass MH - *Disease Management MH - Female MH - Follow-Up Studies MH - Humans MH - Italy/epidemiology MH - Kaplan-Meier Estimate MH - Male MH - Middle Aged MH - Myocardial Infarction/diagnosis/*mortality/therapy MH - Myocardial Reperfusion/*statistics & numerical data MH - Observation MH - Proportional Hazards Models MH - Registries MH - Risk MH - Treatment Outcome FIR - Boccanelli, A IR - Boccanelli A FIR - Giampaoli, S IR - Giampaoli S FIR - Bolognese, L IR - Bolognese L FIR - Chiarella, F IR - Chiarella F FIR - Di Pasquale, G IR - Di Pasquale G FIR - Mafrici, A IR - Mafrici A FIR - Scherillo, M IR - Scherillo M FIR - Schweiger, C IR - Schweiger C FIR - Di Chiara, A IR - Di Chiara A FIR - Maggioni, A P IR - Maggioni AP FIR - Greco, C IR - Greco C FIR - Seccareccia, F IR - Seccareccia F FIR - Lucci, D IR - Lucci D FIR - Gonzini, L IR - Gonzini L FIR - Sarti, L IR - Sarti L FIR - Priami, P IR - Priami P FIR - Spinnler, M T IR - Spinnler MT FIR - Formato, L IR - Formato L FIR - Guillevine, R IR - Guillevine R FIR - Maffiotti, A IR - Maffiotti A FIR - Bobbio, M IR - Bobbio M FIR - Meinardi, F IR - Meinardi F FIR - Vanni, A IR - Vanni A FIR - Dallorto, G IR - Dallorto G FIR - Nassiacos, D IR - Nassiacos D FIR - Pittana, P IR - Pittana P FIR - Klugmann, S IR - Klugmann S FIR - Ferrari, S IR - Ferrari S FIR - Bortolini, F IR - Bortolini F FIR - Rodella, P IR - Rodella P FIR - Romano, M IR - Romano M FIR - Bertona, R IR - Bertona R FIR - Brunazzi, M C IR - Brunazzi MC FIR - Negrelli, M IR - Negrelli M FIR - Rossi, R IR - Rossi R FIR - Carbonieri, E IR - Carbonieri E FIR - Zampiero, A A IR - Zampiero AA FIR - Contessotto, F IR - Contessotto F FIR - Fioretti, P IR - Fioretti P FIR - Di Chiara, A IR - Di Chiara A FIR - Sinagra, G IR - Sinagra G FIR - Maras, P IR - Maras P FIR - Chiarella, F IR - Chiarella F FIR - Rossi, F IR - Rossi F FIR - Domenicucci, S IR - Domenicucci S FIR - Lonati, A IR - Lonati A FIR - Filorizzo, G IR - Filorizzo G FIR - Petacchi, R IR - Petacchi R FIR - Nardi, R IR - Nardi R FIR - Pozzati, A IR - Pozzati A FIR - Pancaldi, L G IR - Pancaldi LG FIR - Capecchi, A IR - Capecchi A FIR - Di Pasquale, G IR - Di Pasquale G FIR - Pavesi, P C IR - Pavesi PC FIR - Pallotti, M G IR - Pallotti MG FIR - Zuppiroli, A IR - Zuppiroli A FIR - Sani, F IR - Sani F FIR - Bolognese, L IR - Bolognese L FIR - Sabini, A IR - Sabini A FIR - Cocchieri, M IR - Cocchieri M FIR - Severini, D IR - Severini D FIR - Patriarchi, F IR - Patriarchi F FIR - Liberati, R IR - Liberati R FIR - Gelibter, D IR - Gelibter D FIR - Palmieri, C IR - Palmieri C FIR - Boccanelli, A IR - Boccanelli A FIR - Greco, C IR - Greco C FIR - Luongo, R IR - Luongo R FIR - Ceci, V IR - Ceci V FIR - Ricci, R IR - Ricci R FIR - Caianiello, G IR - Caianiello G FIR - Bini, A IR - Bini A FIR - Lioy, E IR - Lioy E FIR - Sciahbasi, A IR - Sciahbasi A FIR - Vacri, A IR - Vacri A FIR - De Finis, A IR - De Finis A FIR - Di Nucci, G IR - Di Nucci G FIR - Attademo, G IR - Attademo G FIR - Armogida, N IR - Armogida N FIR - Luca, S IR - Luca S FIR - Prinzi, D IR - Prinzi D FIR - De Rosa, P IR - De Rosa P FIR - Stanco, G IR - Stanco G FIR - Mariello, C IR - Mariello C FIR - Franchini, G IR - Franchini G FIR - Sublimi Saponetti, L IR - Sublimi Saponetti L FIR - Gallone, V IR - Gallone V FIR - Andriulo, C IR - Andriulo C FIR - Pettinati, G IR - Pettinati G FIR - Greco, A IR - Greco A FIR - Tolaro, S IR - Tolaro S FIR - Bottaro, G IR - Bottaro G FIR - Marchi, S M IR - Marchi SM FIR - Meloni, M IR - Meloni M EDAT- 2012/03/29 06:00 MHDA- 2012/08/10 06:00 CRDT- 2012/03/29 06:00 PHST- 2012/03/29 06:00 [entrez] PHST- 2012/03/29 06:00 [pubmed] PHST- 2012/08/10 06:00 [medline] AID - 10.3109/17482941.2012.655296 [doi] PST - ppublish SO - Acute Card Care. 2012 Jun;14(2):71-80. doi: 10.3109/17482941.2012.655296. Epub 2012 Mar 27.