PMID- 22452610 OWN - NLM STAT- MEDLINE DCOM- 20121105 LR - 20160513 IS - 1715-5312 (Print) IS - 1715-5312 (Linking) VI - 37 IP - 2 DP - 2012 Apr TI - Effect of training load on simulated team sport match performance. PG - 315-22 LID - 10.1139/h2012-001 [doi] AB - This study examined the effect of training load on running performance and plasma markers of anaerobic metabolism, muscle damage, and inflammation during a simulated team sport match performance. Seven team sport athletes (maximal oxygen uptake, 47.6 +/- 4.2 mL.kg(-1).min(-1)) completed a 60-min simulated team sport match before and after either 4 days of HIGH or LOW training loads. Venous blood samples were taken pre-match, immediately post-match, and 2 h post-match for interlukin-6, monocyte chemoattractant protein-1 (MCP-1), creatine kinase (CK), lactate dehydrogenase, C-reactive protein, xanthine oxidase (XO), and hypoxanthine. Following HIGH training load, sprint velocity decreased (p < 0.001) and total distance covered was reduced (HIGH 5495 +/- 670 m, LOW 5608 +/- 674 m, p = 0.02) was observed during the simulated match protocol compared with the LOW match simulation. Decreased performance capacity was accompanied by a significant increase in serum CK concentration (HIGH 290 +/- 62 U.L(-1), LOW 199 +/- 33 U.L(-1), p = 0.005). The HIGH training also resulted in a decreased post-match hypoxanthine and MCP-1 and an increase in XO concentration 2 h post-match. Four days of increased training load reduced running performance during the match simulation and altered the metabolic and inflammatory response to high-intensity intermittent exercise. FAU - Slattery, Katie May AU - Slattery KM AD - Human Performance Laboratory, University of Technology Sydney, Lindfield, Australia. katie.m.slattery@uts.edu.au FAU - Wallace, Lee Kenneth AU - Wallace LK FAU - Bentley, David John AU - Bentley DJ FAU - Coutts, Aaron James AU - Coutts AJ LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20120327 PL - Canada TA - Appl Physiol Nutr Metab JT - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme JID - 101264333 RN - 0 (Chemokine CCL2) RN - 0 (Interleukin-6) RN - 2TN51YD919 (Hypoxanthine) RN - 9007-41-4 (C-Reactive Protein) RN - EC 1.1.1.27 (L-Lactate Dehydrogenase) RN - EC 1.17.3.2 (Xanthine Oxidase) RN - EC 2.7.3.2 (Creatine Kinase) SB - IM MH - Adolescent MH - *Athletes MH - *Athletic Performance MH - C-Reactive Protein/metabolism MH - Chemokine CCL2/blood MH - Creatine Kinase/blood MH - Cross-Over Studies MH - Diet MH - Exercise Test/*methods MH - Humans MH - Hypoxanthine/blood MH - Interleukin-6/blood MH - L-Lactate Dehydrogenase/blood MH - Male MH - Oxygen Consumption MH - Running/*physiology MH - Xanthine Oxidase/blood MH - Young Adult EDAT- 2012/03/29 06:00 MHDA- 2012/11/06 06:00 CRDT- 2012/03/29 06:00 PHST- 2012/03/29 06:00 [entrez] PHST- 2012/03/29 06:00 [pubmed] PHST- 2012/11/06 06:00 [medline] AID - 10.1139/h2012-001 [doi] PST - ppublish SO - Appl Physiol Nutr Metab. 2012 Apr;37(2):315-22. doi: 10.1139/h2012-001. Epub 2012 Mar 27.