PMID- 22453664
OWN - NLM
STAT- MEDLINE
DCOM- 20121015
LR  - 20211021
IS  - 1475-1534 (Electronic)
IS  - 1471-4418 (Print)
IS  - 1471-4418 (Linking)
VI  - 21
IP  - 2
DP  - 2012 Jun
TI  - How do dyspnoea scales compare with measurement of functional capacity in 
      patients with COPD and at risk of COPD?
PG  - 202-7
LID - 10.4104/pcrj.2012.00031 [doi]
AB  - BACKGROUND: In primary care, formal functional capacity testing is not always 
      feasible. Guidelines for family practitioners suggest the use of dyspnoea scales 
      to assess exercise tolerance in patients with chronic obstructive pulmonary 
      disease (COPD). AIMS: To examine whether the use of activity-based dyspnoea 
      scales can substitute for actual functional capacity testing. METHODS: 128 
      subjects (49% at risk of COPD, 24% GOLD stage I, 17% GOLD stage II, 9% GOLD stage 
      III) performed an Incremental Shuttle Walk Test (ISWT) and completed the Medical 
      Research Council dyspnoea scale (MRC), Baseline Dyspnoea Index (BDI), Oxygen Cost 
      Diagram (OCD), Clinical COPD Questionnaire (CCQ), and St George's Respiratory 
      Questionnaire (SGRQ). RESULTS: Analysis of variance showed that the relationship 
      between the ISWT and the MRC dyspnoea scale was statistically significant but 
      moderate (p < 0.001, R2 = 0.166). Correlations between the ISWT and the other 
      dyspnoea scales were also moderate (correlation coefficients 0.34-0.42). 
      Combining the dyspnoea scales in one analysis resulted in a proportion of 
      explained variance of the ISWT of 21.4% (R2 = 0.214). CONCLUSIONS: Dyspnoea 
      scales cannot substitute for formal functional capacity testing. Authors of COPD 
      guidelines should consider stating more specifically that the MRC and similar 
      scales measure (self-reported) activity-related dyspnoea but cannot replace 
      objectively measured functional capacity.
FAU - Boer, Lonneke M
AU  - Boer LM
AD  - Department of Medical Psychology, Radboud University Nijmegen Medical Centre, 
      Nijmegen, The Netherlands. L.Boer@mps.umcn.nl
FAU - Asijee, Guus M
AU  - Asijee GM
FAU - van Schayck, Onno C P
AU  - van Schayck OC
FAU - Schermer, Tjard R J
AU  - Schermer TR
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Prim Care Respir J
JT  - Primary care respiratory journal : journal of the General Practice Airways Group
JID - 101121543
SB  - IM
MH  - Activities of Daily Living
MH  - Adult
MH  - Aged
MH  - Analysis of Variance
MH  - Cross-Sectional Studies
MH  - Dyspnea/*diagnosis/physiopathology
MH  - Female
MH  - Forced Expiratory Volume
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pulmonary Disease, Chronic Obstructive/*diagnosis/physiopathology
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Spirometry
MH  - Surveys and Questionnaires
MH  - Vital Capacity
PMC - PMC6547922
COIS- LMB has no conflicts of interest in relation to this article. GMA is an employee 
      of Boehringer Ingelheim b.v. OCPvS is a consultant for Boehringer Ingelheim b.v., 
      AstraZeneca and Pfizer. TRJS is a consultant for Boehringer Ingelheim b.v., GSK 
      and AstraZeneca. OCPvS is an Assistant Editor of, and TRJS an Associate Editor 
      of, the PCRJ; neither were involved in the editorial review of, nor the decision 
      to publish, this article.
EDAT- 2012/03/29 06:00
MHDA- 2012/10/16 06:00
PMCR- 2012/06/01
CRDT- 2012/03/29 06:00
PHST- 2012/03/29 06:00 [entrez]
PHST- 2012/03/29 06:00 [pubmed]
PHST- 2012/10/16 06:00 [medline]
PHST- 2012/06/01 00:00 [pmc-release]
AID - pcrj-2012-02-0015 [pii]
AID - 10.4104/pcrj.2012.00031 [doi]
PST - ppublish
SO  - Prim Care Respir J. 2012 Jun;21(2):202-7. doi: 10.4104/pcrj.2012.00031.