PMID- 2245594
OWN - NLM
STAT- MEDLINE
DCOM- 19910109
LR  - 20190918
IS  - 0144-5979 (Print)
IS  - 0144-5979 (Linking)
VI  - 10
IP  - 5
DP  - 1990 Sep
TI  - Effect of acquisition and analysis routines on gated blood pool measurements.
PG  - 439-50
AB  - Results obtained from gated equilibrium blood pool (GBP) studies are not only
      dependent on intrinsic variations, but also on the way in which images are
      acquired and analysed. The aim of this study was to investigate factors which
      could affect left ventricular time-activity curves. Temporal resolution was
      studied by comparing studies of 20 and 40 frames beat-1. Forty frames per beat
      resulted in a mean left ventricular ejection fraction of 0.48 compared to 0.46
      for 20 frames beat-1. The mean difference of 0.02 was significant (P less than
      0.01) as was the mean difference in maximum emptying rate (MER = 0.28, P less
      than 0.01) and in maximum filling rate (MFR = 0.38, P less than 0.01). No
      significant differences in ejection fraction (EF) values were found between
      acquisitions made in list and frame mode, but the mean differences for MER = 0.03
      (P less than 0.05) and MFR = 0.01 (P less than 0.02) were significant. For
      patient repositioning and intra-observer variations no significant differences
      were found. In patients with normal EF values (greater than 0.5) no significant
      differences were found in the inter-observer study. In patients with anterior
      myocardial infarction (AMI), significant differences were found in EF, MER and
      MFR (EF = 0.02, P less than 0.001; MER = 0.2, P less than 0.01; MFR = 0.24, P
      less than 0.01). Significant differences were found in all values when comparing 
      a semi-automatic method of evaluation with two automatic methods. In conclusion
      the results from this study suggest that acceptable reproducibility can be
      achieved in GBP studies, provided the method of analysis is not changed between
      studies.
FAU - Brodin, L A
AU  - Brodin LA
AD  - Department of Clinical Physiology, Karolinska Hospital, Stockholm, Sweden.
FAU - Bone, D E
AU  - Bone DE
LA  - eng
PT  - Journal Article
PL  - England
TA  - Clin Physiol
JT  - Clinical physiology (Oxford, England)
JID - 8309768
SB  - IM
MH  - Coronary Circulation
MH  - Gated Blood-Pool Imaging/*methods
MH  - Humans
MH  - Observer Variation
MH  - Stroke Volume
MH  - Time Factors
EDAT- 1990/09/01 00:00
MHDA- 1990/09/01 00:01
CRDT- 1990/09/01 00:00
PHST- 1990/09/01 00:00 [pubmed]
PHST- 1990/09/01 00:01 [medline]
PHST- 1990/09/01 00:00 [entrez]
AID - 10.1111/j.1475-097x.1990.tb00824.x [doi]
PST - ppublish
SO  - Clin Physiol. 1990 Sep;10(5):439-50. doi: 10.1111/j.1475-097x.1990.tb00824.x.