PMID- 22456701
OWN - NLM
STAT- MEDLINE
DCOM- 20120815
LR  - 20120329
IS  - 1435-1544 (Electronic)
IS  - 0938-7412 (Linking)
VI  - 23
IP  - 1
DP  - 2012 Mar
TI  - [Commentary on the 2010 ESC guidelines on device therapy in heart failure ].
PG  - 33-7
LID - 10.1007/s00399-011-0158-6 [doi]
AB  - As part of the 2010 focused update of ESC guidelines on device therapy in heart 
      failure, the guidelines on pacemakers in the treatment of heart failure were 
      renewed. A new feature is that cardiac resynchronization therapy (CRT) is 
      indicated for New York Heart Association (NYHA) class III and IV irrespective of 
      the presence of left ventricular dilatation and specified for NYHA class IV 
      (patient ambulatory, stable, life expectancy >6 months). Furthermore, NYHA class 
      II (but not class I) has been added when there is left bundle branch block and 
      QRS duration >/=150 ms. CRT is also indicated for patients in NYHA class III-IV 
      with permanent atrial fibrillation and heart failure [left ventricular ejection 
      fraction (LVEF) </= 35%] when QRS is >/= 130 ms and ventricular rate has slowed 
      either spontaneously or by AV node ablation. In patients with heart failure (NYHA 
      class II-IV, LVEF </= 35%) who need a pacemaker for AV block, CRT is generally 
      indicated to avoid progression of heart failure caused by right ventricular 
      stimulation, also in cases of intrinsic QRS <120 ms. For patients with terminal 
      heart failure who are not eligible for heart transplantation, treatment with a 
      left ventricular assist device can be performed as destination therapy. The new 
      guidelines expand the indication for device therapy in heart failure based on the 
      newest study findings, particularly for patients in NYHA class II, and specify 
      the old guidelines. There are still uncertainties that must be investigated in 
      randomized trials regarding patients with permanent atrial fibrillation, the 
      indication for CRT in heart block, and the question of CRT with pacemaker or 
      defibrillator.
FAU - Israel, C W
AU  - Israel CW
AD  - Klinik fur Innere Medizin - Kardiologie, Diabetologie und Nephrologie, 
      Evangelisches Krankenhaus Bielefeld, Burgsteig 13, 33617 Bielefeld. 
      Carsten.Israel@evkb.de
FAU - Anker, S D
AU  - Anker SD
FAU - Hasenfuss, G
AU  - Hasenfuss G
CN  - European Society of Cardiology
LA  - ger
PT  - English Abstract
PT  - Journal Article
PT  - Practice Guideline
TT  - Kommentar zu den ESC-Leitlinien zur Device-Therapie bei Herzinsuffizienz 2010.
PL  - Germany
TA  - Herzschrittmacherther Elektrophysiol
JT  - Herzschrittmachertherapie & Elektrophysiologie
JID - 9425873
SB  - IM
MH  - Cardiac Resynchronization Therapy/*standards
MH  - Defibrillators, Implantable/*standards
MH  - Europe
MH  - Heart Failure/*prevention & control
MH  - Heart-Assist Devices/*standards
MH  - Humans
MH  - *Practice Guidelines as Topic
EDAT- 2012/03/30 06:00
MHDA- 2012/08/16 06:00
CRDT- 2012/03/30 06:00
PHST- 2012/03/30 06:00 [entrez]
PHST- 2012/03/30 06:00 [pubmed]
PHST- 2012/08/16 06:00 [medline]
AID - 10.1007/s00399-011-0158-6 [doi]
PST - ppublish
SO  - Herzschrittmacherther Elektrophysiol. 2012 Mar;23(1):33-7. doi: 
      10.1007/s00399-011-0158-6.