PMID- 22467910
OWN - NLM
STAT- MEDLINE
DCOM- 20121205
LR  - 20181201
IS  - 1367-4811 (Electronic)
IS  - 1367-4803 (Linking)
VI  - 28
IP  - 10
DP  - 2012 May 15
TI  - AutoLabDB: a substantial open source database schema to support a high-throughput 
      automated laboratory.
PG  - 1390-7
LID - 10.1093/bioinformatics/bts140 [doi]
AB  - MOTIVATION: Modern automated laboratories need substantial data management 
      solutions to both store and make accessible the details of the experiments they 
      perform. To be useful, a modern Laboratory Information Management System (LIMS) 
      should be flexible and easily extensible to support evolving laboratory 
      requirements, and should be based on the solid foundations of a robust, 
      well-designed database. We have developed such a database schema to support an 
      automated laboratory that performs experiments in systems biology and 
      high-throughput screening. RESULTS: We describe the design of the database schema 
      (AutoLabDB), detailing the main features and describing why we believe it will be 
      relevant to LIMS manufacturers or custom builders. This database has been 
      developed to support two large automated Robot Scientist systems over the last 5 
      years, where it has been used as the basis of an LIMS that helps to manage both 
      the laboratory and all the experiment data produced.
FAU - Sparkes, Andrew
AU  - Sparkes A
AD  - Department of Computer Science, Aberystwyth University, Penglais, Aberystwyth, 
      SY23 3DB, UK.
FAU - Clare, Amanda
AU  - Clare A
LA  - eng
GR  - BB/D00425X/1/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
GR  - BB/F008228/1/Biotechnology and Biological Sciences Research Council/United 
      Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120329
PL  - England
TA  - Bioinformatics
JT  - Bioinformatics (Oxford, England)
JID - 9808944
SB  - IM
MH  - Automation, Laboratory
MH  - *Databases, Factual
MH  - *High-Throughput Screening Assays
MH  - *Laboratories
MH  - *Management Information Systems
MH  - Systems Biology
EDAT- 2012/04/03 06:00
MHDA- 2012/12/10 06:00
CRDT- 2012/04/03 06:00
PHST- 2012/04/03 06:00 [entrez]
PHST- 2012/04/03 06:00 [pubmed]
PHST- 2012/12/10 06:00 [medline]
AID - bts140 [pii]
AID - 10.1093/bioinformatics/bts140 [doi]
PST - ppublish
SO  - Bioinformatics. 2012 May 15;28(10):1390-7. doi: 10.1093/bioinformatics/bts140. 
      Epub 2012 Mar 29.