PMID- 22473026 OWN - NLM STAT- MEDLINE DCOM- 20140508 LR - 20130705 IS - 1938-2723 (Electronic) IS - 1076-0296 (Linking) VI - 19 IP - 4 DP - 2013 Jul-Aug TI - Impact of altitude on predicting midterm outcome in patients with ST elevation myocardial infarction. PG - 382-8 LID - 10.1177/1076029612440165 [doi] AB - This study investigated the effects of altitude on occurrence of mid-term negative events among patients presenting with ST elevation myocardial infarction (STEMI). This study enrolled 492 patients with STEMI. 119 of those patients were living at an intermediate altitude (1960 m, Group I) and 373 were living at sea level (0 m, Group II). There was no significant difference between the different altitude groups in terms of the incidence of cardiac death, urgent target vessel revascularization (TVR), stroke/transient ischemic attack (TIA) and composite endpoints. However, Group I had a significantly higher reinfarction incidence when compared with the Group II. Independent predictors of 6-month composite endpoints were history of statin use, presentation with acute stent thrombosis, peak CK-MB level, success of procedure, Killip classification, and left ventricular ejection fraction. In conclusion, altitude status and altitude-related hematologic changes had no influence over the mid-term outcomes in STEMI patients treated with percutaneous intervention. FAU - Isik, Turgay AU - Isik T AD - Department of Cardiology, Balikesir University, School of Medicine, Balikesir, Turkey. isikturgay@yahoo.com FAU - Tanboga, Ibrahim Halil AU - Tanboga IH FAU - Ayhan, Erkan AU - Ayhan E FAU - Uyarel, Huseyin AU - Uyarel H FAU - Kaya, Ahmet AU - Kaya A FAU - Kurt, Mustafa AU - Kurt M FAU - Erdogan, Ercan AU - Erdogan E FAU - Ergelen, Mehmet AU - Ergelen M FAU - Cicek, Gokhan AU - Cicek G FAU - Akgul, Ozgur AU - Akgul O FAU - Ghannadian, Bahman AU - Ghannadian B LA - eng PT - Journal Article DEP - 20120402 PL - United States TA - Clin Appl Thromb Hemost JT - Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis JID - 9508125 SB - IM MH - *Altitude MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*physiopathology/surgery MH - Percutaneous Coronary Intervention MH - Prospective Studies MH - Risk Factors MH - Treatment Outcome OTO - NOTNLM OT - acute coronary syndromes OT - cardiology OT - platelet function EDAT- 2012/04/05 06:00 MHDA- 2014/05/09 06:00 CRDT- 2012/04/05 06:00 PHST- 2012/04/05 06:00 [entrez] PHST- 2012/04/05 06:00 [pubmed] PHST- 2014/05/09 06:00 [medline] AID - 1076029612440165 [pii] AID - 10.1177/1076029612440165 [doi] PST - ppublish SO - Clin Appl Thromb Hemost. 2013 Jul-Aug;19(4):382-8. doi: 10.1177/1076029612440165. Epub 2012 Apr 2.