PMID- 22474593
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20120823
LR  - 20240323
IS  - 2090-4649 (Electronic)
IS  - 2090-4630 (Print)
IS  - 2090-4630 (Linking)
VI  - 2012
DP  - 2012
TI  - Incidence of Metabolic Syndrome and Its Risk Factors among Type 2 Diabetes Clinic 
      Attenders in Isfahan, Iran.
PG  - 167318
LID - 10.5402/2012/167318 [doi]
LID - 167318
AB  - Aim. At present, little data exist about incidence and the risk factors 
      associated with metabolic syndrome (MetS) in patients with type 2 diabetes 
      mellitus (T2DM). The objectives of present study were to assess the incidence and 
      risk factors of MetS in people with T2DM. Methods. During the mean (SD) follow-up 
      period of 11.7 (4.8) years, 3,047 patients with T2DM and free of MetS at baseline 
      have been examined to determine incidence and predictors of progression to MetS. 
      A modified the National Cholesterol Education Program-Adult Treatment Panel III 
      definition with body mass index (BMI) instead of waist circumference was used for 
      the MetS. Results. The prevalence of MetS was 63.2% (95% CI: 62.3, 64.1). The 
      incidence of MetS was 28.5 (95% CI: 26.8, 30.2) (25.9 men and 30.9 women) per 
      1,000 patient-years based on 35,677 patient-years of follow-up. Multivariate 
      analysis revealed that higher BMI and education, lower HbA(1c) and treatment with 
      oral agent or insulin were associated with MetS. Conclusion. These are the first 
      estimate of incidence and risk factors of MetS in patients with T2DM in Iran. 
      These findings showed that the natural course of MetS is dynamic. The clinical 
      management of patients with T2DM will contribute significantly to MetS 
      prevention.
FAU - Janghorbani, Mohsen
AU  - Janghorbani M
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Isfahan 
      University of Medical Sciences, 8144503500 Isfahan, Iran.
FAU - Amini, Masoud
AU  - Amini M
LA  - eng
PT  - Journal Article
DEP - 20120315
PL  - United States
TA  - ISRN Endocrinol
JT  - ISRN endocrinology
JID - 101568096
PMC - PMC3313686
EDAT- 2012/04/05 06:00
MHDA- 2012/04/05 06:01
PMCR- 2012/03/15
CRDT- 2012/04/05 06:00
PHST- 2011/12/05 00:00 [received]
PHST- 2012/01/11 00:00 [accepted]
PHST- 2012/04/05 06:00 [entrez]
PHST- 2012/04/05 06:00 [pubmed]
PHST- 2012/04/05 06:01 [medline]
PHST- 2012/03/15 00:00 [pmc-release]
AID - 10.5402/2012/167318 [doi]
PST - ppublish
SO  - ISRN Endocrinol. 2012;2012:167318. doi: 10.5402/2012/167318. Epub 2012 Mar 15.