PMID- 22477594
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20120823
LR  - 20211021
IS  - 1615-5939 (Electronic)
IS  - 1061-1711 (Print)
IS  - 1061-1711 (Linking)
VI  - 19
IP  - 2
DP  - 2010 Summer
TI  - Predictors of contractile recovery after revascularization in patients with 
      anterior myocardial infarction who received thrombolysis.
PG  - e78-82
AB  - BACKGROUND: Identification of viable myocardium after myocardial infarction has 
      gained paramount importance with the current progress in coronary 
      revascularization. OBJECTIVE: To explore the prognostic power of certain patient 
      characteristics to predict myocardial contractile recovery after 
      revascularization in patients presenting with acute anterior ST elevation 
      myocardial infarction (STEMI) who received thrombolytic therapy. METHODS: 
      Seventy-three consecutive patients presenting with first acute anterior STEMI who 
      had received thrombolytic therapy and had significant coronary stenosis or 
      occlusion of the infarct-related artery amenable for revascularization were 
      enrolled. All patients underwent echocardiographic assessment of regional wall 
      motion and left ventricular ejection fraction. Patients underwent coronary 
      revascularization by either percutaneous angioplasty or surgical bypass. 
      Echocardiography was repeated two to three months following revascularization. 
      Patients were classified into two groups: group 1 had evidence of contractile 
      recovery after revascularization at follow-up echocardiography and group 2 had no 
      such evidence of recovery. RESULTS: Predictors of contractile recovery after 
      revascularization included a shorter time from symptom onset to the institution 
      of thrombolytic therapy, a lower baseline wall motion score index, the presence 
      of grade 3 collaterals to the infarct-related artery and the use of 
      beta-blockers. Instead, the presence of diabetes mellitus and a totally occluded 
      infarct-related artery predicted poor contractile recovery. CONCLUSIONS: 
      Myocardial contractile recovery after revascularization in patients presenting 
      with first acute anterior STEMI may be predicted by the absence of diabetes, a 
      shorter time from symptom onset to thrombolytic therapy, the use of 
      beta-blockers, a lower initial wall motion index score and the presence of 
      collaterals to the infarct-related artery.
FAU - Adel, Walaa
AU  - Adel W
AD  - Cardiology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
FAU - Nammas, Wail
AU  - Nammas W
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Int J Angiol
JT  - The International journal of angiology : official publication of the 
      International College of Angiology, Inc
JID - 9504821
PMC - PMC3005410
EDAT- 2010/07/01 00:00
MHDA- 2010/07/01 00:01
PMCR- 2011/06/01
CRDT- 2012/04/06 06:00
PHST- 2012/04/06 06:00 [entrez]
PHST- 2010/07/01 00:00 [pubmed]
PHST- 2010/07/01 00:01 [medline]
PHST- 2011/06/01 00:00 [pmc-release]
AID - ija19e078 [pii]
AID - 10.1055/s-0031-1278373 [doi]
PST - ppublish
SO  - Int J Angiol. 2010 Summer;19(2):e78-82. doi: 10.1055/s-0031-1278373.