PMID- 22483209
OWN - NLM
STAT- MEDLINE
DCOM- 20120725
LR  - 20171116
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 724
DP  - 2012 Apr 29
TI  - Preparation of Fe3O4 nanoparticle enclosure hydroxylated multi-walled carbon 
      nanotubes for the determination of aconitines in human serum samples.
PG  - 54-60
LID - 10.1016/j.aca.2012.02.039 [doi]
AB  - A magnetic carbon nanomaterial for Fe(3)O(4) enclosure hydroxylated multi-walled 
      carbon nanotubes (Fe(3)O(4)-EC-MWCNTs-OH) was prepared by the aggregating effect 
      of Fe(3)O(4) nanoparticle on MWCNTs-OH, and combined with high-performance liquid 
      chromatography (HPLC)/diode array detection (DAD) to determine the aconitines 
      (aconitine, hypaconitine and mesaconitine) in human serum samples. Compared with 
      other extraction modes investigated in experiment, Fe(3)O(4)-EC-MWCNTs-OH 
      sorbents showed a good affinity to target analytes. Some important parameters 
      that could influence extraction efficiency of aconitines, including the 
      extraction mode, amounts of Fe(3)O(4)-EC-MWCNTs-OH, pH of sample solution, 
      extraction time, desorption solvent and desorption time, were optimized. Under 
      optimal conditions, the recoveries of spiked serum samples were between 98.0% and 
      103.0%; relative standard deviations (RSDs) ranged from 0.9% to 6.2%. The 
      correlation coefficients varied from 0.9996 to 0.9998. The limits of detection 
      ranged from 3.1 ng mL(-1) to 4.1 ng mL(-1) at a signal-to-noise ratio of 3. The 
      experimental results showed that the proposed method was feasible for the 
      analysis of aconitines in serum samples.
CI  - Copyright (c) 2012 Elsevier B.V. All rights reserved.
FAU - Zhang, Hong-Fei
AU  - Zhang HF
AD  - Key Laboratory of Chemistry of Northwestern Plant Resources, Lanzhou Institute of 
      Chemical Physics, Chinese Academy of Sciences, Lanzhou, PR China.
FAU - Shi, Yan-Ping
AU  - Shi YP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120303
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Nanotubes, Carbon)
RN  - 0 (Solvents)
RN  - 5207313N6E (hypaconitine)
RN  - 621OT356HL (mesaconitine)
RN  - X8YN71D5WC (Aconitine)
RN  - XM0M87F357 (Ferrosoferric Oxide)
SB  - IM
MH  - Aconitine/*analogs & derivatives/blood
MH  - Adsorption
MH  - Chromatography, High Pressure Liquid
MH  - Ferrosoferric Oxide/*chemistry
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Limit of Detection
MH  - Microscopy, Electron, Transmission
MH  - Nanoparticles/chemistry/ultrastructure
MH  - Nanotubes, Carbon/*chemistry/ultrastructure
MH  - Serum
MH  - Signal-To-Noise Ratio
MH  - Solid Phase Extraction/*methods
MH  - Solvents
EDAT- 2012/04/10 06:00
MHDA- 2012/07/26 06:00
CRDT- 2012/04/10 06:00
PHST- 2011/12/16 00:00 [received]
PHST- 2012/02/08 00:00 [revised]
PHST- 2012/02/11 00:00 [accepted]
PHST- 2012/04/10 06:00 [entrez]
PHST- 2012/04/10 06:00 [pubmed]
PHST- 2012/07/26 06:00 [medline]
AID - S0003-2670(12)00318-2 [pii]
AID - 10.1016/j.aca.2012.02.039 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2012 Apr 29;724:54-60. doi: 10.1016/j.aca.2012.02.039. Epub 2012 
      Mar 3.