PMID- 22484543
OWN - NLM
STAT- MEDLINE
DCOM- 20120824
LR  - 20191210
IS  - 1872-7972 (Electronic)
IS  - 0304-3940 (Linking)
VI  - 516
IP  - 1
DP  - 2012 May 10
TI  - Brain-derived neurotrophic factor facilitates memory consolidation and 
      reconsolidation of a weak training stimulus in the day-old chick.
PG  - 119-23
LID - 10.1016/j.neulet.2012.03.071 [doi]
AB  - Recent research has pointed to a role for brain-derived neurotrophic factor 
      (BDNF) in long-term potentiation and memory. The present series of experiments 
      examined the effects of the application of exogenous BDNF on memory consolidation 
      and reconsolidation of a weak training stimulus with the day-old chick, using the 
      passive avoidance learning paradigm. Chicks injected intracranially with 12.5 
      mug/mL recombinant BDNF immediately after a single-trial training event displayed 
      enhanced retention relative to saline up to 24h post-training. Furthermore, this 
      dose was also shown to enhance retention when administered following initial weak 
      training. Thus, exogenous BDNF was shown to enhance both consolidation and 
      reconsolidation of memory when administered acutely to the day-old chick.
CI  - Crown Copyright (c) 2012. Published by Elsevier Ireland Ltd. All rights reserved.
FAU - Samartgis, Jodi R
AU  - Samartgis JR
AD  - School of Psychological Science, Faculty of Science, Technology and Engineering, 
      La Trobe University, Bundoora, Victoria 3086, Australia. 
      jrsamartgis@students.latrobe.edu.au
FAU - Schachte, Leslie
AU  - Schachte L
FAU - Hazi, Agnes
AU  - Hazi A
FAU - Crowe, Simon F
AU  - Crowe SF
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120404
PL  - Ireland
TA  - Neurosci Lett
JT  - Neuroscience letters
JID - 7600130
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Animals
MH  - Animals, Newborn
MH  - Avoidance Learning/*drug effects/*physiology
MH  - Brain-Derived Neurotrophic Factor/*pharmacology
MH  - Chickens
MH  - Memory/*drug effects/*physiology
MH  - *Reinforcement, Psychology
EDAT- 2012/04/10 06:00
MHDA- 2012/08/25 06:00
CRDT- 2012/04/10 06:00
PHST- 2011/11/28 00:00 [received]
PHST- 2012/03/13 00:00 [revised]
PHST- 2012/03/26 00:00 [accepted]
PHST- 2012/04/10 06:00 [entrez]
PHST- 2012/04/10 06:00 [pubmed]
PHST- 2012/08/25 06:00 [medline]
AID - S0304-3940(12)00469-7 [pii]
AID - 10.1016/j.neulet.2012.03.071 [doi]
PST - ppublish
SO  - Neurosci Lett. 2012 May 10;516(1):119-23. doi: 10.1016/j.neulet.2012.03.071. Epub 
      2012 Apr 4.