PMID- 22487829
OWN - NLM
STAT- MEDLINE
DCOM- 20120717
LR  - 20120410
IS  - 1003-9406 (Print)
IS  - 1003-9406 (Linking)
VI  - 29
IP  - 2
DP  - 2012 Apr
TI  - [Prognostic value of t(11; 18) (q21; q21) for gastric mucosa-associated lymphoid 
      tissue lymphoma].
PG  - 181-3
LID - 10.3760/cma.j.issn.1003-9406.2012.02.014 [doi]
AB  - OBJECTIVE: To investigate the prognostic value of t(11; 18) (q21; q21) in gastric 
      mucosa-associated lymphoid tissue lymphoma. METHODS: A cohort of thirty-six 
      gastric mucosa-associated lymphoid tissue lymphoma patients who were 
      pathologically identify diagnosis from January 1994 to June 2004 were followed up 
      retrospectively and studied using fluorescence in situ hybridization(FISH) 
      technique to detect t(11; 18) (q21; q21) chromosomal translocation on 
      preservative paraffin specimen. RESULTS: Among thirty-six patients, fifteen 
      (41.67%) were positive for t (11; 18) (q21; q21). All but one were followed up to 
      March 2010, general median survival time (MST) was 87 months. The MST were 43 and 
      130 months for t(11; 18) positive and negative patients, respectively. The MST 
      between these two groups was notably different (chi-square=29.57, P< 0.01). 
      CONCLUSION: t(11; 18) (q21; q21) is important prognostic factor for gastric 
      mucosa-associated lymphoid tissue lymphoma.
FAU - Chen, Tao
AU  - Chen T
AD  - Department of Hematology, Nanjing Medical University, Changzhou, Jiangsu, 
      People's Republic of China. cht71@126.com
FAU - Cen, Ling
AU  - Cen L
FAU - Xiao, Rong
AU  - Xiao R
FAU - Yang, Jian-he
AU  - Yang JH
FAU - Jiang, Nai-ke
AU  - Jiang NK
FAU - Lu, Xu-zhang
AU  - Lu XZ
FAU - Zhang, Yan
AU  - Zhang Y
FAU - Lu, Jing-tao
AU  - Lu JT
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi
JT  - Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese 
      journal of medical genetics
JID - 9425197
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Chromosomes, Human, Pair 11
MH  - *Chromosomes, Human, Pair 18
MH  - Cohort Studies
MH  - Female
MH  - Follow-Up Studies
MH  - Gastric Mucosa/pathology
MH  - Humans
MH  - Lymphoma, B-Cell, Marginal Zone/*genetics/pathology
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Retrospective Studies
MH  - *Translocation, Genetic
EDAT- 2012/04/11 06:00
MHDA- 2012/07/18 06:00
CRDT- 2012/04/11 06:00
PHST- 2012/04/11 06:00 [entrez]
PHST- 2012/04/11 06:00 [pubmed]
PHST- 2012/07/18 06:00 [medline]
AID - 940629044 [pii]
AID - 10.3760/cma.j.issn.1003-9406.2012.02.014 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2012 Apr;29(2):181-3. doi: 
      10.3760/cma.j.issn.1003-9406.2012.02.014.