PMID- 22492829
OWN - NLM
STAT- MEDLINE
DCOM- 20121218
LR  - 20220408
IS  - 1460-2385 (Electronic)
IS  - 0931-0509 (Linking)
VI  - 27
IP  - 7
DP  - 2012 Jul
TI  - Prospective study on clinical effects of renal replacement therapy in 
      treatment-resistant congestive heart failure.
PG  - 2794-9
LID - 10.1093/ndt/gfr756 [doi]
AB  - BACKGROUND/AIMS: Clinical outcome in cardiorenal syndrome (CRS) Type 2 and 
      treatment with dialysis. METHODS: Prospective observational non-randomized study. 
      RESULTS: Twenty-three patients were included, mean age 66+/-21 years. Twelve (52%) 
      patients were treated with peritoneal dialysis (PD) and 11 (48%) with 
      intermittent haemodialysis (IHD). Median survival time after start of dialysis 
      was 16 months. Hospitalizations for cardiovascular causes were reduced (1.4+/-0.6 
      pre-dialysis versus 0.4+/-0.6 days/patient/month post-dialysis, P=0.000), without 
      significant changes in hospitalization for all causes (1.8+/-1.6 versus 2.1+/-2.9 
      days/patient/month). New York Heart Association (NYHA) class (3.8+/-0.4 at start 
      versus 2.4+/-0.7 after 4 months, P=0.000, versus 2.7+/-0.9 after 8 months, P=0.001) 
      and quality of life tended to improve (63+/-21 at start, versus 41+/-20 after 4 
      months, versus 51+/-25 after 8 months; P=0.056). Left ventricular ejection fraction 
      did not change. The number of technical complications associated with dialysis 
      therapy was relatively high in this population. CONCLUSIONS: After starting 
      dialysis for CRS, hospitalizations for cardiovascular causes were reduced, but 
      not hospitalizations for all causes. Functional NYHA class improved and quality 
      of life tended to improve, without evidence for a change in cardiac function. In 
      this small study, no differences between IHD and PD were observed.
FAU - Cnossen, Trijntje T
AU  - Cnossen TT
AD  - Division of Nephrology, Department of Internal Medicine, Maastricht University 
      Medical Center + , Maastricht, The Netherlands. ncnossen@amphia.nl
FAU - Kooman, Jeroen P
AU  - Kooman JP
FAU - Krepel, Harmen P
AU  - Krepel HP
FAU - Konings, Constantijn J A M
AU  - Konings CJ
FAU - Uszko-Lencer, Nicole H M K
AU  - Uszko-Lencer NH
FAU - Leunissen, Karel M L
AU  - Leunissen KM
FAU - van der Sande, Frank M
AU  - van der Sande FM
LA  - eng
PT  - Journal Article
DEP - 20120406
PL  - England
TA  - Nephrol Dial Transplant
JT  - Nephrology, dialysis, transplantation : official publication of the European 
      Dialysis and Transplant Association - European Renal Association
JID - 8706402
SB  - IM
MH  - Aged
MH  - *Drug Resistance
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/mortality/*therapy
MH  - Hospitalization
MH  - Humans
MH  - Male
MH  - Prognosis
MH  - Prospective Studies
MH  - *Renal Dialysis
MH  - *Renal Replacement Therapy
MH  - Survival Rate
EDAT- 2012/04/12 06:00
MHDA- 2012/12/19 06:00
CRDT- 2012/04/12 06:00
PHST- 2012/04/12 06:00 [entrez]
PHST- 2012/04/12 06:00 [pubmed]
PHST- 2012/12/19 06:00 [medline]
AID - gfr756 [pii]
AID - 10.1093/ndt/gfr756 [doi]
PST - ppublish
SO  - Nephrol Dial Transplant. 2012 Jul;27(7):2794-9. doi: 10.1093/ndt/gfr756. Epub 
      2012 Apr 6.