PMID- 22517005 OWN - NLM STAT- MEDLINE DCOM- 20130628 LR - 20221207 IS - 1671-167X (Print) IS - 1671-167X (Linking) VI - 44 IP - 2 DP - 2012 Apr 18 TI - [Relationship of age over 50 years and serum prostate specific antigen in men of Beijing multicentre communities]. PG - 288-90 AB - OBJECTIVE: To investigate the relationship of prostate-specific antigen (PSA) with age in men older than 50 years in Beijing. METHODS: A cross-sectional study was performed in men aged over 50 years at communities in Beijing, and serum total PSA (T-PSA) and free PSA (F-PSA) levels were assayed. The relationship between age and PSA was analyzed with simple linear regression. RESULTS: A total of 1 027 subjects were enrolled. Serum T-PSA and F-PSA levels were positively correlated with age (r=0.208,P<0.001; r=0.230, P<0.001), whereas F/T ratio wasn't correlated with age (r=0.055, P>0.079). The upper limit (95% CI) for serum PSA: 1.55 mug/L for 50-59 years, 2.08 mug/L for 60-69 years, 2.40 mug/L for 70-79 years, 3.52 mug/L for >/=80 years. CONCLUSION: Of the men aged over 50 years in Beijing, there is a positive correlation between serum T-PSA, F-PSA and age; whereas F/T ratio isn't correlated with age. FAU - Li, Xin AU - Li X AD - Department of Urology, Peking University First Hospital, Beijing 100034, China. FAU - Zhang, Xiang-hua AU - Zhang XH FAU - Zhang, Zheng AU - Zhang Z FAU - Li, Shu-qing AU - Li SQ FAU - Lin, Jian AU - Lin J CN - BPC-BPH team LA - chi PT - Journal Article PT - Multicenter Study PL - China TA - Beijing Da Xue Xue Bao Yi Xue Ban JT - Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences JID - 101125284 RN - EC 3.4.21.77 (Prostate-Specific Antigen) SB - IM MH - Age Factors MH - Aged MH - Aged, 80 and over MH - Asian People MH - Cross-Sectional Studies MH - Humans MH - Male MH - Mass Screening/*statistics & numerical data MH - Middle Aged MH - Prostate-Specific Antigen/*blood MH - Prostatic Neoplasms/prevention & control MH - Sampling Studies EDAT- 2012/04/21 06:00 MHDA- 2013/07/03 06:00 CRDT- 2012/04/21 06:00 PHST- 2012/04/21 06:00 [entrez] PHST- 2012/04/21 06:00 [pubmed] PHST- 2013/07/03 06:00 [medline] PST - ppublish SO - Beijing Da Xue Xue Bao Yi Xue Ban. 2012 Apr 18;44(2):288-90.