PMID- 22520945 OWN - NLM STAT- MEDLINE DCOM- 20130614 LR - 20211021 IS - 1750-2659 (Electronic) IS - 1750-2640 (Print) IS - 1750-2640 (Linking) VI - 7 IP - 1 DP - 2013 Jan TI - Safety and tolerability of a 6-week course of oseltamivir prophylaxis for seasonal influenza in children. PG - 11-3 LID - 10.1111/j.1750-2659.2012.00367.x [doi] AB - In an open-label study, 49 children aged 1-12 years received oseltamivir (30-75 mg once daily depending on bodyweight) for 6 weeks for influenza prophylaxis. Seventeen participants reported 22 adverse events (AEs); in three participants, AEs were considered probably drug related (nausea or vomiting). No serious AEs were reported. The tolerability profile was similar to pooled safety data from treatment studies (duration of 5 days) in children. CI - (c) 2012 Blackwell Publishing Ltd. FAU - Reisinger, Keith AU - Reisinger K AD - Primary Physicians Research, Pittsburgh, PA, USA. FAU - Shu, Daniel AU - Shu D FAU - Cupelli, Lisa AU - Cupelli L FAU - Marcadis, Isaac AU - Marcadis I FAU - Dutkowski, Regina AU - Dutkowski R LA - eng SI - ClinicalTrials.gov/NCT00412555 PT - Clinical Trial PT - Journal Article PT - Multicenter Study DEP - 20120423 PL - England TA - Influenza Other Respir Viruses JT - Influenza and other respiratory viruses JID - 101304007 RN - 0 (Antiviral Agents) RN - 20O93L6F9H (Oseltamivir) SB - IM MH - Antiviral Agents/administration & dosage/*adverse effects/*therapeutic use MH - Chemoprevention MH - Child MH - Child, Preschool MH - Female MH - Humans MH - Infant MH - Influenza, Human/*prevention & control MH - Male MH - Oseltamivir/administration & dosage/*adverse effects/*therapeutic use MH - Seasons MH - Treatment Outcome PMC - PMC5780728 EDAT- 2012/04/24 06:00 MHDA- 2013/06/15 06:00 PMCR- 2013/01/01 CRDT- 2012/04/24 06:00 PHST- 2012/04/24 06:00 [entrez] PHST- 2012/04/24 06:00 [pubmed] PHST- 2013/06/15 06:00 [medline] PHST- 2013/01/01 00:00 [pmc-release] AID - IRV367 [pii] AID - 10.1111/j.1750-2659.2012.00367.x [doi] PST - ppublish SO - Influenza Other Respir Viruses. 2013 Jan;7(1):11-3. doi: 10.1111/j.1750-2659.2012.00367.x. Epub 2012 Apr 23.