PMID- 22525626 OWN - NLM STAT- MEDLINE DCOM- 20120813 LR - 20191210 IS - 1646-0758 (Electronic) IS - 0870-399X (Linking) VI - 24 IP - 5 DP - 2011 Sep-Oct TI - [Club drugs]. PG - 739-56 AB - Club drugs are the following substances: Methylenedioxymethamphetamine (MDMA); Methamphetamine; Lysergic Acid Diethylamide (LSD); Ketamine; Gamma-hydroxybutyrate (GHB) and Flunitrazepam. These substances are mainly used by adolescents and young adults, mostly in recreational settings like dance clubs and rave parties. These drugs have diverse psychotropic effects, are associated with several degrees of toxicity, dependence and long term adverse effects. Some have been used for several decades, while others are relatively recent substances of abuse. They have distinct pharmacodynamic and pharmacokinetic properties, are not easy to detect and, many times, the use of club drugs is under diagnosed. Although the use of these drugs is increasingly common, few health professionals feel comfortable with the diagnosis and treatment. The authors performed a systematic literature review, with the goal of synthesising the existing knowledge about club drugs, namely epidemiology, mechanism of action, detection, adverse reactions and treatment. The purpose of this article is creating in Portuguese language a knowledge data base on club drugs, that health professionals of various specialties can use as a reference when dealing with individual with this kind of drug abuse. FAU - Guerreiro, Diogo Frasquilho AU - Guerreiro DF AD - Departamento de Psiquiatria e Saude Mental, Hospital de Santa Maria, Lisboa, Portugal. FAU - Carmo, Ana Lisa AU - Carmo AL FAU - da Silva, Joaquim Alves AU - da Silva JA FAU - Navarro, Rita AU - Navarro R FAU - Gois, Carlos AU - Gois C LA - por PT - Journal Article PT - Review PT - Systematic Review TT - Club drugs: Um Novo Perfil de Abuso de Substancias em Adolescentes e Jovens Adultos. DEP - 20111229 PL - Portugal TA - Acta Med Port JT - Acta medica portuguesa JID - 7906803 RN - 0 (Illicit Drugs) RN - 44RAL3456C (Methamphetamine) RN - 620X0222FQ (Flunitrazepam) RN - 690G0D6V8H (Ketamine) RN - 7G33012534 (Sodium Oxybate) RN - 8NA5SWF92O (Lysergic Acid Diethylamide) RN - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine) SB - IM CIN - Acta Med Port. 2012 Jan-Feb;25(1):60; author reply 60. PMID: 22883253 MH - Adolescent MH - Flunitrazepam/adverse effects/pharmacology MH - Humans MH - *Illicit Drugs/adverse effects/pharmacology MH - Ketamine/adverse effects/pharmacology MH - Lysergic Acid Diethylamide/adverse effects/pharmacology MH - Methamphetamine/adverse effects/pharmacology MH - N-Methyl-3,4-methylenedioxyamphetamine/adverse effects/pharmacology MH - Sodium Oxybate/adverse effects/pharmacology MH - *Substance-Related Disorders/diagnosis/therapy MH - Young Adult EDAT- 2012/04/25 06:00 MHDA- 2012/08/14 06:00 CRDT- 2012/04/25 06:00 PHST- 2009/06/15 00:00 [received] PHST- 2010/03/01 00:00 [accepted] PHST- 2012/04/25 06:00 [entrez] PHST- 2012/04/25 06:00 [pubmed] PHST- 2012/08/14 06:00 [medline] PST - ppublish SO - Acta Med Port. 2011 Sep-Oct;24(5):739-56. Epub 2011 Dec 29.