PMID- 22527213 OWN - NLM STAT- MEDLINE DCOM- 20120824 LR - 20211021 IS - 1435-1250 (Electronic) IS - 0340-1855 (Linking) VI - 71 IP - 3 DP - 2012 Apr TI - [Immune reconstitution syndrome]. PG - 187-98 LID - 10.1007/s00393-011-0858-7 [doi] AB - The immune reconstitution inflammatory syndrome (IRIS) represents a heterogeneous group of conditions. Whilst they typically present in HIV-infected patients with advanced immunodeficiency, IRIS have also been described in HIV-negative patients with immune reconstitution due to other causes of immunosuppression. Frequently IRIS results from an immune response against underlying infection (pathogen-associated IRIS). However, IRIS might become evident during immune reconstitution without an underlying pathogen such as a sarcoid-like illness or an autoimmune thyropathy. Here we report on the epidemiology and risk factors of IRIS along with diagnosis and management of this clinically important inflammatory syndrome. FAU - Meyer-Olson, D AU - Meyer-Olson D AD - Klinik fur Immunologie und Rheumatologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland. meyer-olson.dirk@mh-hannover.de FAU - Ernst, D AU - Ernst D FAU - Stoll, M AU - Stoll M LA - ger PT - English Abstract PT - Journal Article TT - Immunrekonstitutionssyndrome. PL - Germany TA - Z Rheumatol JT - Zeitschrift fur Rheumatologie JID - 0414162 SB - IM MH - HIV Infections/complications/*diagnosis/*therapy MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/complications/*diagnosis/*therapy EDAT- 2012/04/25 06:00 MHDA- 2012/08/25 06:00 CRDT- 2012/04/25 06:00 PHST- 2012/04/25 06:00 [entrez] PHST- 2012/04/25 06:00 [pubmed] PHST- 2012/08/25 06:00 [medline] AID - 10.1007/s00393-011-0858-7 [doi] PST - ppublish SO - Z Rheumatol. 2012 Apr;71(3):187-98. doi: 10.1007/s00393-011-0858-7.