PMID- 22527598
OWN - NLM
STAT- MEDLINE
DCOM- 20120820
LR  - 20220409
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 22
IP  - 6
DP  - 2012 Jun
TI  - Hyperuricemia: a reality in the Indian obese.
PG  - 945-8
LID - 10.1007/s11695-012-0655-7 [doi]
AB  - Hyperuricemia is known to be associated with obesity and metabolic syndrome. The 
      aims of this study were to evaluate the prevalence of hyperuricemia in the Indian 
      obese population and to determine if a correlation exists between hyperuricemia, 
      body mass index, waist circumference and components of metabolic syndrome. This 
      was a retrospective observational study. Four hundred nine obese patients were 
      included. Anthropometric parameters were recorded. Prevalence of type 2 diabetes 
      mellitus (T2DM), hypertension and dyslipidemia were recorded. Uric acid levels 
      were measured in all patients. Hyperuricemia was defined as serum uric acid 
      levels greater than 6 mg/dl. The population studied had a median body mass index 
      (BMI) of 44.14 kg/m(2) (range 28.1-88.2 kg/m(2)) and a median age of 41 years 
      (range 18 to 75 years). Overall prevalence of hyperuricemia was 44.6 %. 
      Thirty-four percent in the BMI range of 28-35 kg/m(2) and 47 % of patients with a 
      BMI of >35 kg/m(2) had hyperuricemia. The incidence of hyperuricemia in males was 
      50 vs 21.7 % in females. Of patients in the hyperuricemia group, 47.3 % had 
      hypertension as compared to 37 % in the normouricemic group. Dyslipidemia was 
      seen in 7.3 % of hyperuricemic patients as compared to 5.8 % of the normouricemic 
      subjects. The prevalence of T2DM was comparable in both the groups. The Indian 
      obese population has a significant high prevalence of hyperuricemia; the 
      incidence of hyperuricemia in male patients was greater than in female patients. 
      Central obesity had no direct link to hyperuricemia. There was no significant 
      correlation between the occurrence of T2DM and dyslipidemia and hyperuricemia. 
      Hypertension was the only comorbidity seen to occur in conjunction with 
      hyperuricemia.
FAU - Remedios, Carlyne
AU  - Remedios C
AD  - Centre for Obesity and Diabetes Surgery, H. Goregaonkar Road, Mumbai, India. 
      carlyne@codsindia.com
FAU - Shah, Miloni
AU  - Shah M
FAU - Bhasker, Aparna Govil
AU  - Bhasker AG
FAU - Lakdawala, Muffazal
AU  - Lakdawala M
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Body Mass Index
MH  - Female
MH  - Humans
MH  - Hypertension/blood
MH  - Hyperuricemia/blood/*epidemiology/etiology
MH  - India/epidemiology
MH  - Male
MH  - Metabolic Syndrome/blood/*epidemiology/etiology
MH  - Middle Aged
MH  - Obesity/blood/complications/*epidemiology
MH  - Prevalence
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Waist Circumference
MH  - Young Adult
EDAT- 2012/04/25 06:00
MHDA- 2012/08/21 06:00
CRDT- 2012/04/25 06:00
PHST- 2012/04/25 06:00 [entrez]
PHST- 2012/04/25 06:00 [pubmed]
PHST- 2012/08/21 06:00 [medline]
AID - 10.1007/s11695-012-0655-7 [doi]
PST - ppublish
SO  - Obes Surg. 2012 Jun;22(6):945-8. doi: 10.1007/s11695-012-0655-7.