PMID- 22530 OWN - NLM STAT- MEDLINE DCOM- 19780218 LR - 20190723 IS - 0021-8820 (Print) IS - 0021-8820 (Linking) VI - 30 IP - 11 DP - 1977 Nov TI - Surface properties of cells of some methicillin-resistant strains of Staphylococcus aureus. PG - 974-9 AB - Methicillin-sensitive (MS) cells of Staphylococcus aureus had a minimum electrophoretic mobility at pH 4.5, whereas methicillin-resistant (MR) strains showed only a slight plateau effect. Trypsin removed the trough effect of the MS Oxford strain. There was no correlation between surface lipid and resistance in MR strains. Cell walls of MS strains contained much more teichoic acid than walls of MR strains. Lysostaphin lysed all MR and MS strains, and mucopeptide does not appear to be involved in resistance to methicillin. FAU - Vernon, G N AU - Vernon GN FAU - Russell, A D AU - Russell AD LA - eng PT - Comparative Study PT - Journal Article PL - England TA - J Antibiot (Tokyo) JT - The Journal of antibiotics JID - 0151115 RN - 0 (Teichoic Acids) RN - EC 3.4.21.4 (Trypsin) RN - EC 3.4.24.75 (Lysostaphin) RN - Q91FH1328A (Methicillin) SB - IM MH - Cell Movement/drug effects MH - Cell Wall/analysis/drug effects MH - Hydrogen-Ion Concentration MH - Lysostaphin/pharmacology MH - *Methicillin MH - Penicillin Resistance MH - Staphylococcus aureus/*cytology/ultrastructure MH - Surface Properties MH - Teichoic Acids/analysis MH - Trypsin/pharmacology EDAT- 1977/11/01 00:00 MHDA- 1977/11/01 00:01 CRDT- 1977/11/01 00:00 PHST- 1977/11/01 00:00 [pubmed] PHST- 1977/11/01 00:01 [medline] PHST- 1977/11/01 00:00 [entrez] AID - 10.7164/antibiotics.30.974 [doi] PST - ppublish SO - J Antibiot (Tokyo). 1977 Nov;30(11):974-9. doi: 10.7164/antibiotics.30.974.