PMID- 22534122
OWN - NLM
STAT- MEDLINE
DCOM- 20120912
LR  - 20161125
IS  - 1879-2448 (Electronic)
IS  - 0043-1354 (Linking)
VI  - 46
IP  - 10
DP  - 2012 Jun 15
TI  - New chlorinated amphetamine-type-stimulants disinfection-by-products formed 
      during drinking water treatment.
PG  - 3304-14
LID - 10.1016/j.watres.2012.03.029 [doi]
AB  - Previous studies have demonstrated high removal rates of 
      amphetamine-type-stimulants (ATSs) through conventional drinking water 
      treatments; however the behaviour of these compounds through disinfection steps 
      and their transformation into disinfection-by-products (DBPs) is still unknown. 
      In this work, for the first time, the reactivity of some ATSs such as 
      amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine (MDA), 
      3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyethylamphetamine 
      (MDEA) with chlorine has been investigated under simulated and real drinking 
      water treatment conditions in order to evaluate their ability to give rise to 
      transformation products. Two new DBPs from these illicit drugs have been found. A 
      common chlorinated-by-product (3-chlorobenzo)-1,3-dioxole, was identified for 
      both MDA and MDEA while for MDMA, 3-chlorocatechol was found. The presence of 
      these DBPs in water samples collected through drinking water treatment was 
      studied in order to evaluate their formation under real conditions. Both 
      compounds were generated through treatment from raw river water samples 
      containing ATSs at concentration levels ranging from 1 to 15 ng/L for MDA and 
      from 2.3 to 78 ng/L for MDMA. One of them, (3-chlorobenzo)-1,3-dioxole, found 
      after the first chlorination step, was eliminated after ozone and GAC treatment 
      while the MDMA DBP mainly generated after the postchlorination step, showed to be 
      recalcitrant and it was found in final treated waters at concentrations ranging 
      from 0.5 to 5.8 ng/L.
CI  - Copyright (c) 2012 Elsevier Ltd. All rights reserved.
FAU - Huerta-Fontela, Maria
AU  - Huerta-Fontela M
AD  - AGBAR-Aigues de Barcelona, General Batet 5-7, 08028 Barcelona, Spain.
FAU - Pineda, Oriol
AU  - Pineda O
FAU - Ventura, Francesc
AU  - Ventura F
FAU - Galceran, Maria Teresa
AU  - Galceran MT
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120402
PL  - England
TA  - Water Res
JT  - Water research
JID - 0105072
RN  - 0 (Amphetamines)
RN  - 0 (Central Nervous System Stimulants)
RN  - 0 (Drinking Water)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
RN  - ML1I4KK67B (3,4-methylenedioxyethamphetamine)
SB  - IM
MH  - 3,4-Methylenedioxyamphetamine/analogs & derivatives/chemistry
MH  - Amphetamines/*chemistry
MH  - Central Nervous System Stimulants/*chemistry
MH  - *Disinfection
MH  - Drinking Water/*chemistry
MH  - *Halogenation
MH  - N-Methyl-3,4-methylenedioxyamphetamine/chemistry
MH  - Spain
MH  - Spectrometry, Mass, Electrospray Ionization
MH  - Water Purification/*methods
MH  - Water Quality
EDAT- 2012/04/27 06:00
MHDA- 2012/09/13 06:00
CRDT- 2012/04/27 06:00
PHST- 2011/12/12 00:00 [received]
PHST- 2012/03/13 00:00 [revised]
PHST- 2012/03/14 00:00 [accepted]
PHST- 2012/04/27 06:00 [entrez]
PHST- 2012/04/27 06:00 [pubmed]
PHST- 2012/09/13 06:00 [medline]
AID - S0043-1354(12)00192-3 [pii]
AID - 10.1016/j.watres.2012.03.029 [doi]
PST - ppublish
SO  - Water Res. 2012 Jun 15;46(10):3304-14. doi: 10.1016/j.watres.2012.03.029. Epub 
      2012 Apr 2.