PMID- 22534401
OWN - NLM
STAT- MEDLINE
DCOM- 20130114
LR  - 20221207
IS  - 1873-7714 (Electronic)
IS  - 0163-8343 (Linking)
VI  - 34
IP  - 5
DP  - 2012 Sep-Oct
TI  - Citalopram-induced subacute cutaneous lupus erythematosus -- first case and 
      review concerning photosensitivity in selective serotonin reuptake inhibitors.
PG  - 541-5
LID - 10.1016/j.genhosppsych.2012.03.012 [doi]
AB  - OBJECTIVE: This report describes a case of subacute cutaneous lupus erythematosus 
      (SCLE) in a patient treated with citalopram and discusses evidence linking 
      selective serotonin reuptake inhibitors (SSRIs) to the induction of 
      photosensitivity. METHOD: Case report and review of published literature. 
      RESULTS: A 71-year-old woman with major depression developed 2 days after intake 
      of 20 mg citalopram a strongly itching and largely dimensioned confluencing 
      erythema with infiltrations and blisters all over the trunk with fever and 
      malaise. Histological and laboratory investigations were consistent with the 
      diagnosis of SCLE. After stopping citalopram intake, dermatologic symptoms 
      significantly improved within 2 weeks. SSRIs have been associated with 14 cases 
      of adverse cutaneous events as a result of SSRI-induced photosensitivity. No case 
      of SSRI-induced SCLE has been described. CONCLUSION: In clinical practice, 
      indication and dosage of citalopram and other SSRIs should be carefully 
      monitored. In the case of a SSRI-induced photosensitivity, medication can be 
      switched to an antidepressant from another class.
CI  - Copyright (c) 2012 Elsevier Inc. All rights reserved.
FAU - Rohrs, Susanne
AU  - Rohrs S
AD  - Department of Psychosomatic Medicine and Psychotherapy, University of Bonn, 53105 
      Bonn, Germany.
FAU - Geiser, Franziska
AU  - Geiser F
FAU - Conrad, Rupert
AU  - Conrad R
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20120424
PL  - United States
TA  - Gen Hosp Psychiatry
JT  - General hospital psychiatry
JID - 7905527
RN  - 0 (Serotonin Uptake Inhibitors)
RN  - 0DHU5B8D6V (Citalopram)
SB  - IM
MH  - Aged
MH  - Citalopram/administration & dosage/*adverse effects
MH  - Female
MH  - Germany
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/*chemically induced/physiopathology
MH  - Photosensitivity Disorders/*chemically induced
MH  - Selective Serotonin Reuptake Inhibitors/administration & dosage/*adverse effects
MH  - Treatment Outcome
EDAT- 2012/04/27 06:00
MHDA- 2013/01/15 06:00
CRDT- 2012/04/27 06:00
PHST- 2012/01/06 00:00 [received]
PHST- 2012/03/14 00:00 [revised]
PHST- 2012/03/16 00:00 [accepted]
PHST- 2012/04/27 06:00 [entrez]
PHST- 2012/04/27 06:00 [pubmed]
PHST- 2013/01/15 06:00 [medline]
AID - S0163-8343(12)00082-5 [pii]
AID - 10.1016/j.genhosppsych.2012.03.012 [doi]
PST - ppublish
SO  - Gen Hosp Psychiatry. 2012 Sep-Oct;34(5):541-5. doi: 
      10.1016/j.genhosppsych.2012.03.012. Epub 2012 Apr 24.