PMID- 22537332
OWN - NLM
STAT- MEDLINE
DCOM- 20120814
LR  - 20211021
IS  - 1542-474X (Electronic)
IS  - 1082-720X (Print)
IS  - 1082-720X (Linking)
VI  - 17
IP  - 2
DP  - 2012 Apr
TI  - PR depression is useful in the differential diagnosis of myopericarditis and ST 
      elevation myocardial infarction.
PG  - 141-5
LID - 10.1111/j.1542-474X.2012.00489.x [doi]
AB  - BACKGROUND: Deviation of the PR segment is a common but often ignored ECG finding 
      in acute myopericarditis, but seems to be rare in the acute phase of ST elevation 
      myocardial infarction (STEMI). Since rapid bedside differential diagnosis of 
      acute myopericarditis and STEMI is essential, we decided to assess the diagnostic 
      power of PR depressions in patients presenting with ST elevations in the 
      emergency room. METHODS: Thirty-four consecutive patients with acute 
      myopericarditis and 46 STEMI patients presenting with ST elevations fulfilling 
      the criteria for STEMI were included. The first ECG recorded in the emergency 
      room was analyzed with a focus on the PR segment. The diagnoses of 
      myopericarditis and STEMI were ascertained with clinical follow-up together with 
      rise in troponin levels, and in the STEMI patients also with coronary 
      angiography. RESULTS: In myopericarditis, the most common location for PR 
      depression was lead II (55.9%), while this ECG finding least likely appeared in 
      lead aVL (2.9%). PR depression in any lead had a high sensitivity (88.2%), but 
      fairly low specificity (78.3%) for myopericarditis. The combination of PR 
      depressions in both precordial and limb leads had the most favorable predictive 
      power to differentiate myopericarditis from STEMI (positive 96.7% and negative 
      power 90%). CONCLUSIONS: Our present observations show that PR segment analysis 
      is a powerful tool in the differential diagnosis of myopericarditis and STEMI. 
      This simple information should be added to the diagnostic workup of patients 
      presenting with ST elevations.
CI  - (c) 2012, Wiley Periodicals, Inc.
FAU - Porela, Pekka
AU  - Porela P
AD  - Department of Medicine, Turku University Hospital, Finland. pekka.porela@tyks.fi
FAU - Kyto, Ville
AU  - Kyto V
FAU - Nikus, Kjell
AU  - Nikus K
FAU - Eskola, Markku
AU  - Eskola M
FAU - Airaksinen, K E J
AU  - Airaksinen KE
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Ann Noninvasive Electrocardiol
JT  - Annals of noninvasive electrocardiology : the official journal of the 
      International Society for Holter and Noninvasive Electrocardiology, Inc
JID - 9607443
SB  - IM
MH  - Acute Disease
MH  - Adolescent
MH  - Adult
MH  - Coronary Angiography
MH  - Diagnosis, Differential
MH  - Electrocardiography/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnosis/physiopathology
MH  - Myocarditis/*diagnosis/physiopathology
MH  - Pericarditis/*diagnosis/physiopathology
MH  - Predictive Value of Tests
MH  - Sensitivity and Specificity
PMC - PMC6931962
EDAT- 2012/04/28 06:00
MHDA- 2012/08/15 06:00
PMCR- 2012/04/26
CRDT- 2012/04/28 06:00
PHST- 2012/04/28 06:00 [entrez]
PHST- 2012/04/28 06:00 [pubmed]
PHST- 2012/08/15 06:00 [medline]
PHST- 2012/04/26 00:00 [pmc-release]
AID - ANEC489 [pii]
AID - 10.1111/j.1542-474X.2012.00489.x [doi]
PST - ppublish
SO  - Ann Noninvasive Electrocardiol. 2012 Apr;17(2):141-5. doi: 
      10.1111/j.1542-474X.2012.00489.x.