PMID- 22538473 OWN - NLM STAT- MEDLINE DCOM- 20140124 LR - 20220330 IS - 1436-3771 (Electronic) IS - 1432-6981 (Linking) VI - 17 IP - 2 DP - 2013 Mar TI - The influence of bone substitute materials on the bone volume after maxillary sinus augmentation: a microcomputerized tomography study. PG - 543-51 LID - 10.1007/s00784-012-0732-2 [doi] AB - OBJECTIVES: This study aims to evaluate the effect of adding bone substitute materials (BSM) to particulated autogenous bone (PAB) on the volume fraction (Vf) of newly formed bone after maxillary sinus augmentation. MATERIALS AND METHODS: Thirty healthy patients undergoing maxillary sinus augmentation were included. PAB (N = 10), mixtures of PAB and beta-tricalciumphosphate (PAB/beta-TCP) (N = 10), as well as PAB and beta-TCP and hydroxyapatite (PAB/HA/beta-TCP) (N = 10) were randomly used for sinus augmentation. A sample of the graft material was maintained from each patient at time of maxillary sinus augmentation, and Vfs of the PAB and/or BSM in the samples were determined by means of microcomputerized tomography (mu-CT). Five months later, samples of the grafted areas were harvested during implantation using a trephine bur. mu-CT analysis of these samples was performed, and the Vf of bone and BSM were compared with the data obtained 5 months earlier from the original material. RESULTS: The mean Vf of the bone showed a statistically significant increase (p < 0.05) in all groups after a healing period of 5 months without statistically significant difference between the groups. CONCLUSIONS: With regard to the increase of bone volume, it is not relevant if PAB is used alone or combined with beta-TCP or HA/beta-TCP. CLINICAL RELEVANCE: The amount of PAB and associated donor site morbidity may be reduced by adding BSM for maxillary sinus augmentation. FAU - Kuhl, Sebastian AU - Kuhl S AD - School of Dental Medicine, Department of Oral Surgery, Oral Radiology and Oral Medicine, University of Basel, Hebelstrasse 3, 4056 Basel, Switzerland. sebastian.kuehl@unibas.ch FAU - Brochhausen, Christoph AU - Brochhausen C FAU - Gotz, Hermann AU - Gotz H FAU - Filippi, Andreas AU - Filippi A FAU - Payer, Michael AU - Payer M FAU - d'Hoedt, Bernd AU - d'Hoedt B FAU - Kreisler, Matthias AU - Kreisler M LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20120427 PL - Germany TA - Clin Oral Investig JT - Clinical oral investigations JID - 9707115 RN - 0 (Bone Substitutes) RN - 0 (Calcium Phosphates) RN - 0 (beta-tricalcium phosphate) RN - 91D9GV0Z28 (Durapatite) MH - Adult MH - Aged MH - Autografts/diagnostic imaging/pathology/transplantation MH - Bone Density/*physiology MH - Bone Substitutes/*therapeutic use MH - Bone Transplantation/methods MH - Calcium Phosphates/therapeutic use MH - Durapatite/therapeutic use MH - Female MH - Follow-Up Studies MH - Humans MH - Image Processing, Computer-Assisted/methods MH - Imaging, Three-Dimensional/methods MH - Male MH - Maxilla/diagnostic imaging/pathology MH - Maxillary Sinus/diagnostic imaging/pathology MH - Middle Aged MH - Osteogenesis/physiology MH - Sinus Floor Augmentation/*methods MH - X-Ray Microtomography/*methods EDAT- 2012/04/28 06:00 MHDA- 2014/01/25 06:00 CRDT- 2012/04/28 06:00 PHST- 2011/10/13 00:00 [received] PHST- 2012/04/09 00:00 [accepted] PHST- 2012/04/28 06:00 [entrez] PHST- 2012/04/28 06:00 [pubmed] PHST- 2014/01/25 06:00 [medline] AID - 10.1007/s00784-012-0732-2 [doi] PST - ppublish SO - Clin Oral Investig. 2013 Mar;17(2):543-51. doi: 10.1007/s00784-012-0732-2. Epub 2012 Apr 27.