PMID- 22546392 OWN - NLM STAT- MEDLINE DCOM- 20120702 LR - 20131121 IS - 1527-9995 (Electronic) IS - 0090-4295 (Linking) VI - 79 IP - 5 DP - 2012 May TI - Comparison of harmful gases produced during GreenLight High-Performance System laser prostatectomy and transurethral resection of the prostate. PG - 1118-24 LID - 10.1016/j.urology.2011.11.071 [doi] AB - OBJECTIVE: To compare the gases generated from GreenLight High-Performance System (HPS) laser prostatectomy with Urosol or normal saline solution and transurethral resection and vaporization of the prostate (TURVP) with Urosol. METHODS: A total of 36 smoke samples were collected from a continuous irrigation suction system attached to a Tenax absorber during transurethral surgery of the prostate. The gases were qualitatively and quantitatively analyzed by gas chromatography-mass spectrometry equipped with a purge and trap sample injector. RESULTS: The gas produced during TURVP contained propylene, allene, isobutylene, 1,3-butadiene, vinyl acetylene, mercaptomethane, ethyl acetylene, diacetylene, 1-pentene, ethanol, piperylene, propenylacetylene, 1,4-pentadiene, cyclopentadiene, acrylnitrile, and butyrolacton. The types and amount of gas produced during HPS laser prostatectomy were fewer and smaller than during TURVP. However, 1,3-butadiene, a well-known human carcinogen, was also generated by HPS laser prostatectomy. HPS laser prostatectomy with saline produced a greater amount and number of gases than HPS laser prostatectomy with Urosol. CONCLUSION: The surgical smoke produced from TURVP and HPS laser prostatectomy contains potentially harmful chemical compounds, although HPS laser prostatectomy produced less surgical smoke than TURVP. Urosol produced fewer types and a smaller amount of gas than normal saline during HPS laser prostatectomy. CI - Copyright (c) 2012 Elsevier Inc. All rights reserved. FAU - Park, Seung Chol AU - Park SC AD - Department of Urology, Wonkwang University School of Medicine and Hospital, Iksan, Korea. FAU - Lee, Sang Kyi AU - Lee SK FAU - Han, Suk Hee AU - Han SH FAU - Chung, Yun Jo AU - Chung YJ FAU - Park, Jong Kwan AU - Park JK LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Urology JT - Urology JID - 0366151 RN - 0 (Alkenes) RN - 0 (Butadienes) RN - 0 (Cyclopentanes) RN - 0 (Gases) RN - 0 (Hazardous Substances) RN - 0 (Smoke) RN - 3K9958V90M (Ethanol) RN - JSD5FGP5VD (1,3-butadiene) SB - IM CIN - Urology. 2012 May;79(5):1124-5; author reply 1125. PMID: 22546393 MH - Aged MH - Alkenes/*analysis MH - Butadienes/analysis MH - Cyclopentanes/analysis MH - Ethanol/analysis MH - Gas Chromatography-Mass Spectrometry MH - Gases/*chemistry MH - Hazardous Substances/analysis MH - Humans MH - *Laser Therapy MH - Male MH - Middle Aged MH - Prospective Studies MH - Prostatectomy/*methods MH - *Smoke MH - *Transurethral Resection of Prostate EDAT- 2012/05/02 06:00 MHDA- 2012/07/03 06:00 CRDT- 2012/05/02 06:00 PHST- 2011/10/19 00:00 [received] PHST- 2011/11/29 00:00 [revised] PHST- 2011/11/29 00:00 [accepted] PHST- 2012/05/02 06:00 [entrez] PHST- 2012/05/02 06:00 [pubmed] PHST- 2012/07/03 06:00 [medline] AID - S0090-4295(12)00100-8 [pii] AID - 10.1016/j.urology.2011.11.071 [doi] PST - ppublish SO - Urology. 2012 May;79(5):1118-24. doi: 10.1016/j.urology.2011.11.071.