PMID- 22548125 OWN - NLM STAT- MEDLINE DCOM- 20120716 LR - 20211021 IS - 1748-6718 (Electronic) IS - 1748-670X (Print) IS - 1748-670X (Linking) VI - 2012 DP - 2012 TI - Multiple Subject Barycentric Discriminant Analysis (MUSUBADA): how to assign scans to categories without using spatial normalization. PG - 634165 LID - 10.1155/2012/634165 [doi] LID - 634165 AB - We present a new discriminant analysis (DA) method called Multiple Subject Barycentric Discriminant Analysis (MUSUBADA) suited for analyzing fMRI data because it handles datasets with multiple participants that each provides different number of variables (i.e., voxels) that are themselves grouped into regions of interest (ROIs). Like DA, MUSUBADA (1) assigns observations to predefined categories, (2) gives factorial maps displaying observations and categories, and (3) optimally assigns observations to categories. MUSUBADA handles cases with more variables than observations and can project portions of the data table (e.g., subtables, which can represent participants or ROIs) on the factorial maps. Therefore MUSUBADA can analyze datasets with different voxel numbers per participant and, so does not require spatial normalization. MUSUBADA statistical inferences are implemented with cross-validation techniques (e.g., jackknife and bootstrap), its performance is evaluated with confusion matrices (for fixed and random models) and represented with prediction, tolerance, and confidence intervals. We present an example where we predict the image categories (houses, shoes, chairs, and human, monkey, dog, faces,) of images watched by participants whose brains were scanned. This example corresponds to a DA question in which the data table is made of subtables (one per subject) and with more variables than observations. FAU - Abdi, Herve AU - Abdi H AD - School of Behavioral and Brain Sciences, University of Texas at Dallas, MS: GR4.1, 800 West Campbell Road, Richardson, TX 75080-3021, USA. herve@utdallas.edu FAU - Williams, Lynne J AU - Williams LJ FAU - Connolly, Andrew C AU - Connolly AC FAU - Gobbini, M Ida AU - Gobbini MI FAU - Dunlop, Joseph P AU - Dunlop JP FAU - Haxby, James V AU - Haxby JV LA - eng PT - Journal Article DEP - 20120405 PL - United States TA - Comput Math Methods Med JT - Computational and mathematical methods in medicine JID - 101277751 SB - IM MH - Animals MH - Brain/*physiology MH - Data Interpretation, Statistical MH - Discriminant Analysis MH - Dogs MH - Face MH - Female MH - Haplorhini MH - Humans MH - Magnetic Resonance Imaging/*psychology MH - Male PMC - PMC3328164 EDAT- 2012/05/02 06:00 MHDA- 2012/07/17 06:00 PMCR- 2012/04/05 CRDT- 2012/05/02 06:00 PHST- 2011/09/30 00:00 [received] PHST- 2011/12/20 00:00 [revised] PHST- 2011/12/21 00:00 [accepted] PHST- 2012/05/02 06:00 [entrez] PHST- 2012/05/02 06:00 [pubmed] PHST- 2012/07/17 06:00 [medline] PHST- 2012/04/05 00:00 [pmc-release] AID - 10.1155/2012/634165 [doi] PST - ppublish SO - Comput Math Methods Med. 2012;2012:634165. doi: 10.1155/2012/634165. Epub 2012 Apr 5.