PMID- 22550563
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20211021
IS  - 2035-3006 (Electronic)
IS  - 2035-3006 (Linking)
VI  - 4
IP  - 1
DP  - 2012
TI  - Adjuvant corticosteroid therapy in hepatosplenic candidiasis-related iris.
PG  - e2012018
LID - 10.4084/MJHID.2012.018 [doi]
LID - e2012018
AB  - Candida infections are the most frequent infections in neutropenic patients. 
      Hepatosplenic candidiasis (HSC) is a part of disseminated Candida infection that 
      occurs most commonly in patients with hematologic malignancies treated with 
      chemotherapy and requires protracted antifungal therapy. During invasive mycosis 
      with rapid resolution of immunosuppression, immune reconstitution inflammatory 
      syndrome (IRIS) which mimics treatment failure, drug toxicity or breakthrough 
      infections may occur. Manifestation period, histopathologic findings and 
      favorable effect of steroids to its inflammatory symptoms strongly suggest that 
      HSC belongs to the invasive fungal infection induced IRIS. We present a child 
      with B cell-acute lymphoblastic leukemia who developed HSC and addition of 
      corticosteroid therapy to antifungal treatment achieved rapid resolution of the 
      clinical symptoms and laboratory findings.
FAU - Bayram, Cengiz
AU  - Bayram C
AD  - Department of Pediatric Hematology, Ankara Children's Hematology and Oncology 
      Hospital, Ankara, Turkey.
FAU - Fettah, Ali
AU  - Fettah A
FAU - Yarali, Nese
AU  - Yarali N
FAU - Kara, Abdurrahman
AU  - Kara A
FAU - Azik, Fatih Mehmet
AU  - Azik FM
FAU - Tavil, Betul
AU  - Tavil B
FAU - Tunc, Bahattin
AU  - Tunc B
LA  - eng
PT  - Case Reports
DEP - 20120313
PL  - Italy
TA  - Mediterr J Hematol Infect Dis
JT  - Mediterranean journal of hematology and infectious diseases
JID - 101530512
PMC - PMC3340993
EDAT- 2012/05/03 06:00
MHDA- 2012/05/03 06:01
PMCR- 2012/01/01
CRDT- 2012/05/03 06:00
PHST- 2011/12/07 00:00 [received]
PHST- 2012/02/02 00:00 [accepted]
PHST- 2012/05/03 06:00 [entrez]
PHST- 2012/05/03 06:00 [pubmed]
PHST- 2012/05/03 06:01 [medline]
PHST- 2012/01/01 00:00 [pmc-release]
AID - mjhid-4-1-e2012018 [pii]
AID - 10.4084/MJHID.2012.018 [doi]
PST - ppublish
SO  - Mediterr J Hematol Infect Dis. 2012;4(1):e2012018. doi: 10.4084/MJHID.2012.018. 
      Epub 2012 Mar 13.