PMID- 22551927
OWN - NLM
STAT- MEDLINE
DCOM- 20130214
LR  - 20120914
IS  - 1873-5010 (Electronic)
IS  - 1569-1993 (Linking)
VI  - 11
IP  - 5
DP  - 2012 Sep
TI  - Prevalence of cystic fibrosis pathogens in the oropharynx of healthy children and 
      implications for cystic fibrosis care.
PG  - 456-7
LID - S1569-1993(12)00054-9 [pii]
LID - 10.1016/j.jcf.2012.04.004 [doi]
AB  - OBJECTIVE: To describe the prevalence of the CF pathogens Pseudomonas aeruginosa, 
      Staphylococcus aureus and Haemophilus influenzae in OP cultures from healthy 
      children. METHODS: Oropharyngeal (OP) swabs were collected from 100 healthy 
      children </=18 years of age undergoing a clinically indicated procedure. RESULTS: 
      P. aeruginosa was isolated from the OP swab of one participant, S. aureus from 48 
      participants (including 4 methicillin-resistant) and H. influenzae from 47 
      participants. Cultures from 75 participants grew one or more of these organisms 
      (55 grew one, 19 grew 2 and one grew 3 organisms). CONCLUSION: P. aeruginosa is 
      rarely recovered from the oropharynx of healthy children </=18 years of age, while 
      recovery of S. aureus and H. influenzae is common. It is important to understand 
      what the "normal" prevalence of CF pathogens is in the oropharynx in order to aid 
      interpretation of OP cultures in CF patients.
CI  - Copyright (c) 2012 European Cystic Fibrosis Society. Published by Elsevier B.V. All 
      rights reserved.
FAU - Rosenfeld, Margaret
AU  - Rosenfeld M
AD  - Division of Pulmonary Medicine, Seattle Children's Hospital, Seattle, WA 98105, 
      USA. Margaret.rosenfeld@seattlechildrens.org
FAU - Bernardo-Ocampo, Carmen
AU  - Bernardo-Ocampo C
FAU - Emerson, Julia
AU  - Emerson J
FAU - Genatossio, Alan
AU  - Genatossio A
FAU - Burns, Jane
AU  - Burns J
FAU - Gibson, Ron
AU  - Gibson R
LA  - eng
PT  - Journal Article
DEP - 20120430
PL  - Netherlands
TA  - J Cyst Fibros
JT  - Journal of cystic fibrosis : official journal of the European Cystic Fibrosis 
      Society
JID - 101128966
SB  - IM
MH  - Bacteriological Techniques/methods
MH  - Child
MH  - Cystic Fibrosis/epidemiology/*microbiology
MH  - Female
MH  - Haemophilus influenzae/*isolation & purification
MH  - Humans
MH  - Male
MH  - Oropharynx/*microbiology
MH  - Prevalence
MH  - Pseudomonas aeruginosa/*isolation & purification
MH  - *Respiratory Tract Infections/diagnosis/epidemiology/microbiology
MH  - Staphylococcus aureus/*isolation & purification
MH  - Washington/epidemiology
EDAT- 2012/05/04 06:00
MHDA- 2013/02/15 06:00
CRDT- 2012/05/04 06:00
PHST- 2012/02/08 00:00 [received]
PHST- 2012/04/05 00:00 [revised]
PHST- 2012/04/05 00:00 [accepted]
PHST- 2012/05/04 06:00 [entrez]
PHST- 2012/05/04 06:00 [pubmed]
PHST- 2013/02/15 06:00 [medline]
AID - S1569-1993(12)00054-9 [pii]
AID - 10.1016/j.jcf.2012.04.004 [doi]
PST - ppublish
SO  - J Cyst Fibros. 2012 Sep;11(5):456-7. doi: 10.1016/j.jcf.2012.04.004. Epub 2012 
      Apr 30.