PMID- 22555278
OWN - NLM
STAT- MEDLINE
DCOM- 20121024
LR  - 20220317
IS  - 1468-3296 (Electronic)
IS  - 0040-6376 (Linking)
VI  - 67
IP  - 9
DP  - 2012 Sep
TI  - The development and validation of the King's Brief Interstitial Lung Disease 
      (K-BILD) health status questionnaire.
PG  - 804-10
LID - 10.1136/thoraxjnl-2012-201581 [doi]
AB  - RATIONALE: Health status is impaired in patients with interstitial lung disease 
      (ILD). There is a paucity of tools that assess health status in ILD. The 
      objective of this study was to develop and validate the King's Brief Interstitial 
      Lung Disease questionnaire (K-BILD), a new health status measure for patients 
      with ILD. METHODS: Patients with ILD were recruited from outpatient clinics. The 
      development of the questionnaire consisted of three phases: item generation; item 
      reduction, allocation to domains by factor analysis, Rasch analysis to create 
      unidimensional scales and validation; and repeatability testing. RESULTS: 173 
      patients with ILD (49 with idiopathic pulmonary fibrosis) completed a preliminary 
      71-item questionnaire. 56 items were removed due to redundancy, low factor 
      loadings or poor fit to the Rasch model. The final version of the K-BILD 
      questionnaire consisted of 15 items and three domains (breathlessness and 
      activities, chest symptoms and psychological). Internal consistency assessed with 
      Cronbach's alpha coefficient was 0.94 for the K-BILD total score. Concurrent validity 
      of the K-BILD questionnaire was high compared with St George's Respiratory 
      Questionnaire (r=0.90) and moderate with lung function (vital capacity, r=0.50). 
      The K-BILD questionnaire was repeatable over 2 weeks (n=44), with intraclass 
      correlation coefficients for domains and total score 0.86-0.94. The K-BILD 
      construct validity for patients with idiopathic pulmonary fibrosis was similar to 
      that of other ILDs. CONCLUSION: The K-BILD questionnaire is a brief, valid, 
      self-completed health status measure for ILD. It could be used in the clinic to 
      assess ILD from the patients' perspective.
FAU - Patel, Amit S
AU  - Patel AS
AD  - Division of Asthma, Allergy and Lung Biology, King's College London, Denmark 
      Hill, London SE5 9RS, UK.
FAU - Siegert, Richard J
AU  - Siegert RJ
FAU - Brignall, Katherine
AU  - Brignall K
FAU - Gordon, Patrick
AU  - Gordon P
FAU - Steer, Sophia
AU  - Steer S
FAU - Desai, Sujal R
AU  - Desai SR
FAU - Maher, Toby M
AU  - Maher TM
FAU - Renzoni, Elisabetta A
AU  - Renzoni EA
FAU - Wells, Athol U
AU  - Wells AU
FAU - Higginson, Irene J
AU  - Higginson IJ
FAU - Birring, Surinder S
AU  - Birring SS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20120503
PL  - England
TA  - Thorax
JT  - Thorax
JID - 0417353
SB  - IM
MH  - Chi-Square Distribution
MH  - Female
MH  - *Health Status
MH  - Humans
MH  - London
MH  - Lung Diseases, Interstitial/*physiopathology
MH  - Male
MH  - Predictive Value of Tests
MH  - Severity of Illness Index
MH  - *Surveys and Questionnaires
EDAT- 2012/05/05 06:00
MHDA- 2012/10/25 06:00
CRDT- 2012/05/05 06:00
PHST- 2012/05/05 06:00 [entrez]
PHST- 2012/05/05 06:00 [pubmed]
PHST- 2012/10/25 06:00 [medline]
AID - thoraxjnl-2012-201581 [pii]
AID - 10.1136/thoraxjnl-2012-201581 [doi]
PST - ppublish
SO  - Thorax. 2012 Sep;67(9):804-10. doi: 10.1136/thoraxjnl-2012-201581. Epub 2012 May 
      3.