PMID- 22555329
OWN - NLM
STAT- MEDLINE
DCOM- 20120731
LR  - 20181201
IS  - 0026-4946 (Print)
IS  - 0026-4946 (Linking)
VI  - 64
IP  - 3
DP  - 2012 Jun
TI  - Nonconvulsive status epilepticus in pediatric populations: diagnosis and 
      management.
PG  - 347-55
AB  - The diagnosis and management of nonconvulsive status epilepticus (NCSE) pose 
      special challenges in childhood. NCSE can be defined as a condition of ongoing or 
      intermittent clinical epileptic activity without convulsions, for at least 30 
      minutes, with electroencephalographic evidence of seizures. NCSE accounts for 
      approximately one-quarter of all cases of status epilepticus. NCSE should be 
      suspected in children with epilepsy who undergo an otherwise inexplicable change 
      in behavior and in children with recent onset change in speech, memory, school 
      performance. NCSE can be observed in acute neurological injuries, specific 
      childhood epilepsy syndromes, individuals with learning difficulties and other 
      neurological conditions. NCSE is not uncommon in pediatric patients with an 
      altered state of consciousness. NCSE in children is thought to be 
      under-recognized. It is a highly heterogeneous clinical condition that is 
      understudied in the pediatric population. Prompt recognition and treatment may be 
      necessary to improve neurological outcome. Based on clinical semiology alone, 
      diagnosis is difficult and requires emergent EEG. Management is often difficult, 
      with highly variable response to treatment. Here I describe the diagnosis and 
      management of NCSE in children.
FAU - Galimi, R
AU  - Galimi R
AD  - Department of Neurology, Health Local Unit of Valtellina and Valchiavenna, 
      Sondalo Hospital, Sondrio, Italy. glrocco@tiscalinet.it
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Italy
TA  - Minerva Pediatr
JT  - Minerva pediatrica
JID - 0400740
RN  - 0 (Anticonvulsants)
RN  - 12794-10-4 (Benzodiazepines)
RN  - 2MRO291B4U (Clobazam)
RN  - 614OI1Z5WI (Valproic Acid)
RN  - O26FZP769L (Lorazepam)
RN  - O3FX965V0I (Acetazolamide)
SB  - IM
MH  - Acetazolamide/therapeutic use
MH  - Anticonvulsants/administration & dosage/*therapeutic use
MH  - Benzodiazepines/therapeutic use
MH  - Child
MH  - Clobazam
MH  - Electroencephalography
MH  - Humans
MH  - Lorazepam/therapeutic use
MH  - Status Epilepticus/*diagnosis/*drug therapy
MH  - Treatment Outcome
MH  - Valproic Acid/therapeutic use
EDAT- 2012/05/05 06:00
MHDA- 2012/08/01 06:00
CRDT- 2012/05/05 06:00
PHST- 2012/05/05 06:00 [entrez]
PHST- 2012/05/05 06:00 [pubmed]
PHST- 2012/08/01 06:00 [medline]
AID - R15123484 [pii]
PST - ppublish
SO  - Minerva Pediatr. 2012 Jun;64(3):347-55.