PMID- 22564579
OWN - NLM
STAT- MEDLINE
DCOM- 20120904
LR  - 20120508
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Linking)
VI  - 44
IP  - 4
DP  - 2012 May
TI  - Steroid pulse therapy combined with plasmapheresis for clinically compromised 
      patients after heart transplantation.
PG  - 900-2
LID - 10.1016/j.transproceed.2012.01.086 [doi]
AB  - BACKGROUND: The most serious complication after heart transplantation is 
      allograft dysfunction. Patients presenting with compromised hemodynamics show a 
      high incidence of mortality. The most common reason for allograft dysfunction is 
      rejection. We have employed steroid pulse therapy combined with plasmapheresis 
      for hemodynamically compromised patients after heart transplantation. METHODS AND 
      RESULTS: Steroid pulse therapy and plasmapheresis were performed on 35 patients 
      who underwent orthotopic heart transplantation for graft dysfunction. Thus 
      treatment rescued ventricular function and improved the ejection fraction in 77% 
      of patients, among who ever 71.4% showed improved New York Heart Association 
      (NYHA) functional class. CONCLUSIONS: Steroid pulse therapy combined with 
      plasmapheresis improved the cardiac contractility and NYHA functional class of 
      most heart transplant recipients with graft dysfunction.
CI  - Copyright (c) 2012 Elsevier Inc. All rights reserved.
FAU - Chou, H-W
AU  - Chou HW
AD  - Department of Surgery, National Taiwan University Hospital and National Taiwan 
      University College of Medicine, Taipei, Taiwan.
FAU - Chi, N-H
AU  - Chi NH
FAU - Lin, M-H
AU  - Lin MH
FAU - Chou, N-K
AU  - Chou NK
FAU - Tsao, C-I
AU  - Tsao CI
FAU - Yu, H-Y
AU  - Yu HY
FAU - Chen, Y-S
AU  - Chen YS
FAU - Wang, S-S
AU  - Wang SS
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
RN  - 0 (Immunosuppressive Agents)
RN  - 0 (Steroids)
SB  - IM
MH  - Combined Modality Therapy
MH  - Graft Rejection/etiology/mortality/physiopathology/*therapy
MH  - Heart Diseases/etiology/mortality/physiopathology/*therapy
MH  - Heart Transplantation/*adverse effects/mortality
MH  - Hemodynamics
MH  - Hospital Mortality
MH  - Humans
MH  - Immunosuppressive Agents/*administration & dosage
MH  - Myocardial Contraction
MH  - *Plasmapheresis
MH  - Pulse Therapy, Drug
MH  - Steroids/*administration & dosage
MH  - Stroke Volume
MH  - Taiwan
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ventricular Function, Left
EDAT- 2012/05/09 06:00
MHDA- 2012/09/05 06:00
CRDT- 2012/05/09 06:00
PHST- 2012/05/09 06:00 [entrez]
PHST- 2012/05/09 06:00 [pubmed]
PHST- 2012/09/05 06:00 [medline]
AID - S0041-1345(12)00121-2 [pii]
AID - 10.1016/j.transproceed.2012.01.086 [doi]
PST - ppublish
SO  - Transplant Proc. 2012 May;44(4):900-2. doi: 10.1016/j.transproceed.2012.01.086.