PMID- 22573237
OWN - NLM
STAT- MEDLINE
DCOM- 20130708
LR  - 20161125
IS  - 1460-2385 (Electronic)
IS  - 0931-0509 (Linking)
VI  - 27
IP  - 9
DP  - 2012 Sep
TI  - Chest ultrasound and hidden lung congestion in peritoneal dialysis patients.
PG  - 3601-5
LID - 10.1093/ndt/gfs116 [doi]
AB  - BACKGROUND: Chest ultrasound (US) is a non-invasive well-validated technique for 
      estimating extravascular lung water (LW) in patients with heart diseases and in 
      end-stage renal disease. We systematically applied this technique to the whole 
      peritoneal dialysis (PD) population of five dialysis units. METHODS: We studied 
      the cross-sectional association between LW, echocardiographic parameters, 
      clinical [pedal oedema, New York Heart Association (NYHA) class] and 
      bioelectrical impedance analysis (BIA) markers of volume status in 88 PD 
      patients. RESULTS: Moderate to severe lung congestion was evident in 41 (46%) 
      patients. Ejection fraction was the echocardiographic parameter with the 
      strongest independent association with LW (r = -0.40 P = 0.002). Oedema did not 
      associate with LW on univariate and multivariate analysis. NYHA class was 
      slightly associated with LW (r = 0.21 P = 0.05). Among patients with severe lung 
      congestion, only 27% had pedal oedema and the majority (57%) had no dyspnoea 
      (NYHA Class I). Similarly, the prevalence of patients with BIA, evidence of 
      volume excess was small (11%) and not significantly different (P = 0.79) from 
      that observed in patients with mild or no congestion (9%). CONCLUSIONS: In PD 
      patients, LW by chest US reveals moderate to severe lung congestion in a 
      significant proportion of asymptomatic patients. Intervention studies are 
      necessary to prove the usefulness of chest US for optimizing the control of fluid 
      excess in PD patients.
FAU - Panuccio, Vincenzo
AU  - Panuccio V
AD  - Nephrology, Dialysis, Hypertension and Renal Transplantation Unit, Ospedali 
      Riuniti, Reggio Calabria, Italy.
FAU - Enia, Giuseppe
AU  - Enia G
FAU - Tripepi, Rocco
AU  - Tripepi R
FAU - Torino, Claudia
AU  - Torino C
FAU - Garozzo, Maurizio
AU  - Garozzo M
FAU - Battaglia, Giovanni Giorgio
AU  - Battaglia GG
FAU - Marcantoni, Carmelita
AU  - Marcantoni C
FAU - Infantone, Lorena
AU  - Infantone L
FAU - Giordano, Guido
AU  - Giordano G
FAU - De Giorgi, Maria Loreta
AU  - De Giorgi ML
FAU - Lupia, Mario
AU  - Lupia M
FAU - Bruzzese, Vincenzo
AU  - Bruzzese V
FAU - Zoccali, Carmine
AU  - Zoccali C
LA  - eng
PT  - Journal Article
DEP - 20120509
PL  - England
TA  - Nephrol Dial Transplant
JT  - Nephrology, dialysis, transplantation : official publication of the European 
      Dialysis and Transplant Association - European Renal Association
JID - 8706402
RN  - 0 (Biomarkers)
SB  - IM
MH  - Aged
MH  - Biomarkers/analysis
MH  - Cross-Sectional Studies
MH  - Echocardiography
MH  - *Electric Impedance
MH  - Extravascular Lung Water/*metabolism
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Kidney Failure, Chronic/*complications/therapy
MH  - Male
MH  - Middle Aged
MH  - Peritoneal Dialysis/*adverse effects
MH  - Prognosis
MH  - Pulmonary Edema/diagnosis/*etiology
MH  - Risk Factors
MH  - Thorax/*diagnostic imaging
EDAT- 2012/05/11 06:00
MHDA- 2013/07/09 06:00
CRDT- 2012/05/11 06:00
PHST- 2012/05/11 06:00 [entrez]
PHST- 2012/05/11 06:00 [pubmed]
PHST- 2013/07/09 06:00 [medline]
AID - gfs116 [pii]
AID - 10.1093/ndt/gfs116 [doi]
PST - ppublish
SO  - Nephrol Dial Transplant. 2012 Sep;27(9):3601-5. doi: 10.1093/ndt/gfs116. Epub 
      2012 May 9.