PMID- 22575394 OWN - NLM STAT- MEDLINE DCOM- 20130114 LR - 20121029 IS - 1532-821X (Electronic) IS - 0003-9993 (Linking) VI - 93 IP - 11 DP - 2012 Nov TI - Test-retest reliability of the 6-minute walk test in individuals with Down syndrome. PG - 2068-74 LID - S0003-9993(12)00318-8 [pii] LID - 10.1016/j.apmr.2012.04.022 [doi] AB - OBJECTIVES: To evaluate the reliability of the 6-minute walk test (6MWT) in individuals with Down syndrome and explore factors affecting walking distance. DESIGN: Four repeated walk tests in the span of 2 weeks including 2 practice walks. SETTING: All tests were carried out in a 40-meter corridor at a university sport complex. PARTICIPANTS: Adolescents and young adults with Down syndrome (N=55) aged 11 to 26 years. INTERVENTION: Not applicable. MAIN OUTCOME MEASURE: Participants were instructed to walk as far as possible for the duration of 6 minutes. Distance walked, heart rate, blood pressure, and perceived exertion were measured across 4 tests (t1, t2, t3, and t4). RESULTS: The walking distances for t1, t2, t3, and t4 averaged 395, 428, 433, and 436 meters, respectively. The 6-minute walk distance (6MWD) during t1 and t2 was significantly different from that during t3 and t4 (t(54)=-6.475, P<.001). Repeated analysis of variance showed no significant difference between the distance walked in t3 and t4 (433+/-64m vs 436+/-68m) (F(1,54)=2.439, P=.124). Body mass index as well as levels of intellectual disability and physical activity all affected the distance walked to different degrees. CONCLUSIONS: The 6MWT showed good test-retest reliability and increased the walking distance after 2 practice walks, emphasizing the need to account for a learning effect among people with Down syndrome. Reported 6MWD appears lower than that previously reported for individuals without Down syndrome. CI - Copyright (c) 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved. FAU - Casey, Amanda F AU - Casey AF AD - Department of Human Kinetics, St Francis Xavier University, Antigonish, NS, Canada. acasey@stfx.ca FAU - Wang, Xu AU - Wang X FAU - Osterling, Kristin AU - Osterling K LA - eng PT - Journal Article DEP - 20120507 PL - United States TA - Arch Phys Med Rehabil JT - Archives of physical medicine and rehabilitation JID - 2985158R SB - IM MH - Adolescent MH - Adult MH - Child MH - Down Syndrome/*rehabilitation MH - Exercise Test/*methods MH - Female MH - Humans MH - Male MH - Reproducibility of Results MH - *Walking MH - Young Adult EDAT- 2012/05/12 06:00 MHDA- 2013/01/15 06:00 CRDT- 2012/05/12 06:00 PHST- 2012/02/27 00:00 [received] PHST- 2012/04/27 00:00 [revised] PHST- 2012/04/28 00:00 [accepted] PHST- 2012/05/12 06:00 [entrez] PHST- 2012/05/12 06:00 [pubmed] PHST- 2013/01/15 06:00 [medline] AID - S0003-9993(12)00318-8 [pii] AID - 10.1016/j.apmr.2012.04.022 [doi] PST - ppublish SO - Arch Phys Med Rehabil. 2012 Nov;93(11):2068-74. doi: 10.1016/j.apmr.2012.04.022. Epub 2012 May 7.