PMID- 22581879 OWN - NLM STAT- MEDLINE DCOM- 20120905 LR - 20120514 IS - 1758-1052 (Electronic) IS - 0956-4624 (Linking) VI - 23 IP - 3 DP - 2012 Mar TI - Nodal cryptococcal immune reconstitution inflammatory syndrome masquerading as tuberculosis in an HIV-infected patient. PG - 216-8 LID - 10.1258/ijsa.2009.009356 [doi] AB - An African HIV-infected patient presented with widespread necrotic lymphadenopathy five months after starting combination antiretroviral therapy (cART) and was thought to have disseminated tuberculosis in the context of an immune reconstitution inflammatory syndrome (IRIS) on the basis of typical imaging appearances and suggestive appearances from a fine needle aspirate of a nodal mass. The patient deteriorated despite empirical antituberculosis therapy and the correct diagnosis of nodal cryptococcal infection was subsequently established by histological examination of a core biopsy from a lymph node. IRIS should be borne in mind when considering the differential diagnosis in a patient who has recently started cART. FAU - Tweddle, A AU - Tweddle A AD - T8, University College London Hospitals Foundation Trust, University College London, London, UK. FAU - Davies, S J AU - Davies SJ FAU - Topping, W AU - Topping W FAU - Whitehorn, J AU - Whitehorn J FAU - Falzon, M AU - Falzon M FAU - Miller, R F AU - Miller RF LA - eng PT - Case Reports PT - Journal Article PL - England TA - Int J STD AIDS JT - International journal of STD & AIDS JID - 9007917 SB - IM MH - Adult MH - Biopsy, Fine-Needle MH - Cryptococcosis/*diagnosis/immunology/pathology MH - Diagnosis, Differential MH - Female MH - HIV Infections/*complications/*drug therapy MH - Histocytochemistry MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/*diagnosis/pathology MH - Lymph Nodes/*pathology MH - Lymphatic Diseases/diagnosis/*etiology MH - Radiography, Thoracic MH - Tomography, X-Ray Computed MH - Tuberculosis/*diagnosis/pathology EDAT- 2012/05/15 06:00 MHDA- 2012/09/06 06:00 CRDT- 2012/05/15 06:00 PHST- 2012/05/15 06:00 [entrez] PHST- 2012/05/15 06:00 [pubmed] PHST- 2012/09/06 06:00 [medline] AID - 23/3/216 [pii] AID - 10.1258/ijsa.2009.009356 [doi] PST - ppublish SO - Int J STD AIDS. 2012 Mar;23(3):216-8. doi: 10.1258/ijsa.2009.009356.