PMID- 22588193
OWN - NLM
STAT- MEDLINE
DCOM- 20130801
LR  - 20220316
IS  - 1434-4726 (Electronic)
IS  - 0937-4477 (Linking)
VI  - 270
IP  - 2
DP  - 2013 Feb
TI  - Spa therapy of upper respiratory tract inflammations.
PG  - 565-70
LID - 10.1007/s00405-012-2024-5 [doi]
AB  - The upper airway respiratory diseases (i.e. common cold, allergic rhinitis, 
      nonallergic/vasomotor rhinitis, acute and chronic rhinosinusitis and nasal 
      polyposis) in which nasal congestion is a common symptom are often undertreated 
      due to the frequent inadequate efficacy and safety concern with current 
      therapies. In scientific literature, few studies seem to support the hypothesis 
      that nasal inhalatory treatment with thermal water promotes the improvement of 
      nasal symptoms, even if the mechanisms by which the improvement from SPA therapy 
      can be expected remain debated. A prospective comparative study with a pre-post 
      design has been performed consecutively enrolling 33 (males 70 %) patients of 
      both genders older than 12 years of age, affected by chronic sinonasal 
      inflammation. All patients underwent a 14-days course of radioactive water warm 
      vapour inhalations followed by nasal aerosol of the same thermal water 10 min 
      each once/day at Merano Therme. At the beginning and end of the study, in all the 
      subjects, nasal function evaluation by active anterior rhinomanometry, 
      mucociliary transport time (MCTt) determination and nasal cytology were 
      performed. After the inhalatory treatment, the mucociliary function was improved 
      and the pathologic mucociliary transport times recorded at the beginning of the 
      study being significantly reduced to physiologic ones. Besides, before treatment, 
      the cytologic picture showed an inflammatory cell infiltration (eosinophils, 
      neutrophils with/without bacteria, mast cells) in 37 % of patients; after therapy 
      in 66 % of these patients, the rhinocytogram was normal. Our results suggest, 
      according to the literature data, that SPA therapy with radioactive water could 
      represent an alternative choice in chronic inflammatory diseases of the upper 
      airways, nonresponsive to pharmacological therapy.
FAU - Passali, D
AU  - Passali D
AD  - University of Siena Medical School, Siena, Italy. d.passali@virgilio.it
FAU - De Corso, E
AU  - De Corso E
FAU - Platzgummer, S
AU  - Platzgummer S
FAU - Streitberger, C
AU  - Streitberger C
FAU - Lo Cunsolo, S
AU  - Lo Cunsolo S
FAU - Nappi, G
AU  - Nappi G
FAU - Passali, G C
AU  - Passali GC
FAU - Bellussi, L
AU  - Bellussi L
LA  - eng
PT  - Journal Article
DEP - 20120516
PL  - Germany
TA  - Eur Arch Otorhinolaryngol
JT  - European archives of oto-rhino-laryngology : official journal of the European 
      Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the 
      German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
SB  - IM
MH  - *Balneology
MH  - Chronic Disease
MH  - Female
MH  - Humans
MH  - Male
MH  - Mucociliary Clearance
MH  - Nasal Mucosa/pathology
MH  - Nasal Obstruction/etiology
MH  - Rhinitis/complications/physiopathology/*therapy
MH  - Sinusitis/complications/physiopathology/*therapy
EDAT- 2012/05/17 06:00
MHDA- 2013/08/02 06:00
CRDT- 2012/05/17 06:00
PHST- 2012/01/20 00:00 [received]
PHST- 2012/04/19 00:00 [accepted]
PHST- 2012/05/17 06:00 [entrez]
PHST- 2012/05/17 06:00 [pubmed]
PHST- 2013/08/02 06:00 [medline]
AID - 10.1007/s00405-012-2024-5 [doi]
PST - ppublish
SO  - Eur Arch Otorhinolaryngol. 2013 Feb;270(2):565-70. doi: 
      10.1007/s00405-012-2024-5. Epub 2012 May 16.