PMID- 22591982
OWN - NLM
STAT- MEDLINE
DCOM- 20130516
LR  - 20120626
IS  - 1872-8464 (Electronic)
IS  - 0165-5876 (Linking)
VI  - 76
IP  - 8
DP  - 2012 Aug
TI  - Surgical treatment of paediatric cholesteatoma: long-term follow up in comparison 
      with adults.
PG  - 1091-7
LID - 10.1016/j.ijporl.2012.04.006 [doi]
AB  - OBJECTIVE: This study was designed to analyse long-term results after surgery of 
      acquired (ACH) and congenital cholesteatoma (CCH) of the middle ear in children 
      and compare these with adults. METHODS: Computer-based analysis of consecutively 
      operated paediatric patients for ACH and CCH in a tertiary referral centre was 
      made in 57 cases under the age of 12 operated 1983-2004 by three surgeons using 
      identical technique. A canal wall down and total reconstruction procedure (TRP) 
      with obliteration of the mastoid cavity, canal wall reconstruction, 
      ossiculoplasty with consistent use of autologous bone and an "aeration 
      enhancement procedure" (AEP) with silicon sheet in selected cases were used. Pre- 
      and post-operative PTA (0.5-3 kHz) and pure-tone average air-bone gap (PTA-ABG) 
      together with surgical parameters were assessed 1, 3 and 6 years following 
      surgery. RESULTS: Results showed stable hearing over 6 years with low incidence 
      of persistent and recurrent disease comparable with results from adult patients. 
      In nearly half of the cases, silastic sheeting was used. In 21 cases, stapes was 
      eroded. Bone conduction thresholds levels remained unaffected 6 years after 
      surgery. No deaf ears, postoperative facial dysfunction or other lesions related 
      to surgery were observed. Six years after surgery every evaluated ear was found 
      to be water-resistant and infection -free. CONCLUSION: Our results suggest that 
      one-stage eradication of ACH and CCH in children using total reconstruction 
      procedure (TRP) provide long-term improvement or preservation of hearing, with a 
      low incidence of persistent or recurrent disease. No difference in surgical 
      outcome between children and adults was found.
CI  - Copyright (c) 2012 Elsevier Ireland Ltd. All rights reserved.
FAU - Edfeldt, Lennart
AU  - Edfeldt L
AD  - Department of Otolaryngology, Uppsala University Hospital, 75185 Uppsala, Sweden. 
      lennart.edfeldt@akademiska.se
FAU - Kinnefors, Anders
AU  - Kinnefors A
FAU - Stromback, Karin
AU  - Stromback K
FAU - Kobler, Susanne
AU  - Kobler S
FAU - Rask-Andersen, Helge
AU  - Rask-Andersen H
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120514
PL  - Ireland
TA  - Int J Pediatr Otorhinolaryngol
JT  - International journal of pediatric otorhinolaryngology
JID - 8003603
SB  - IM
MH  - Adult
MH  - Audiometry
MH  - Child
MH  - Child, Preschool
MH  - Cholesteatoma, Middle Ear/*surgery
MH  - Ear, Middle/*pathology/surgery
MH  - Follow-Up Studies
MH  - Hearing
MH  - Humans
MH  - Postoperative Period
MH  - Treatment Outcome
EDAT- 2012/05/18 06:00
MHDA- 2013/05/17 06:00
CRDT- 2012/05/18 06:00
PHST- 2012/01/17 00:00 [received]
PHST- 2012/04/02 00:00 [revised]
PHST- 2012/04/07 00:00 [accepted]
PHST- 2012/05/18 06:00 [entrez]
PHST- 2012/05/18 06:00 [pubmed]
PHST- 2013/05/17 06:00 [medline]
AID - S0165-5876(12)00244-3 [pii]
AID - 10.1016/j.ijporl.2012.04.006 [doi]
PST - ppublish
SO  - Int J Pediatr Otorhinolaryngol. 2012 Aug;76(8):1091-7. doi: 
      10.1016/j.ijporl.2012.04.006. Epub 2012 May 14.