PMID- 22594006
OWN - NLM
STAT- MEDLINE
DCOM- 20120619
LR  - 20120518
IS  - 1660-9379 (Print)
IS  - 1660-9379 (Linking)
VI  - 8
IP  - 337
DP  - 2012 Apr 18
TI  - [Hypersensitivity to proton pump inhibitors].
PG  - 830-5
AB  - Hypersensitivity to proton pump inhibitors (PPI) is rare but potentially severe. 
      An increase in hypersensitivity reactions to PPI is expected as these drugs are 
      widely prescribed and some have become available over-the-counter. Allergy to PPI 
      has to be considered in patients presenting anaphylaxis, late-type skin rashes, 
      interstitial nephritis and other organ involvement suspicious to be drug-induced. 
      Cross-reactivity between PPI is of concern, as they are closely related in 
      structure. Skin prick- and intradermal testing are reliable tools to confirm 
      immediate-type allergy to one PPI compound and search for safe alternatives. We 
      review the literature on immediate and delayed hypersensitivity to these drugs.
FAU - Bergmann, M
AU  - Bergmann M
AD  - Service d'allergologie et immunologie clinique, HUG, 1211 Geneve 14. 
      marcel.bergmann@hcuge.ch
FAU - Guignard, B
AU  - Guignard B
FAU - Ribi, C
AU  - Ribi C
LA  - fre
PT  - English Abstract
PT  - Journal Article
TT  - Hypersensibilite aux inhibiteurs de la pompe a protons.
PL  - Switzerland
TA  - Rev Med Suisse
JT  - Revue medicale suisse
JID - 101219148
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Algorithms
MH  - Drug Hypersensitivity/*diagnosis/*etiology
MH  - Humans
MH  - Molecular Structure
MH  - Proton Pump Inhibitors/*adverse effects/chemistry
MH  - Skin Tests
EDAT- 2012/05/19 06:00
MHDA- 2012/06/20 06:00
CRDT- 2012/05/19 06:00
PHST- 2012/05/19 06:00 [entrez]
PHST- 2012/05/19 06:00 [pubmed]
PHST- 2012/06/20 06:00 [medline]
PST - ppublish
SO  - Rev Med Suisse. 2012 Apr 18;8(337):830-5.