PMID- 22605866
OWN - NLM
STAT- MEDLINE
DCOM- 20130212
LR  - 20211021
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 2012
DP  - 2012 May 8
TI  - Acute paradoxical reaction of cervical tuberculous lymphadenitis prompted by a 
      misuse of etimicin sulphate.
LID - 10.1136/bcr.12.2011.5458 [doi]
LID - bcr1220115458
AB  - A 45-year-old HIV-negative man was treated with intravenous etimicin sulphate for 
      an unintentionally found, non-tender neck mass at a local outpatient clinic. His 
      symptoms seemed improved initially. However, the unilateral mass subsequently 
      became enlarged quickly and painful. Spontaneous discharge occurred after 
      admission to our department. The smear of the pus from surgical drainage was 
      positive for acid-fast bacilli and the presence of Mycobacterium tuberculosis was 
      confirmed by culture. He was diagnosed with an acute paradoxical reaction (PR) of 
      cervical tuberculous lymphadenitis. Our case was unusual in that acute PR of 
      tuberculosis was caused by receiving single aminoglycoside agent which has not 
      been proven to have therapeutic effect on TB infection and it is also the first 
      case of PR induced by etimicin. The patient recovered well from a 6-month 
      antituberculosis chemotherapy.
FAU - Jiao, Yang
AU  - Jiao Y
AD  - Department of General Internal Medicine, Peking Union Medical College Hospital & 
      Chinese Academy of Medical Sciences, Beijing, China. peterpumc@hotmail.com
FAU - Chen, Jialin
AU  - Chen J
FAU - Zeng, Xuejun
AU  - Zeng X
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120508
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Anti-Inflammatory Agents, Non-Steroidal)
RN  - 0 (Antitubercular Agents)
RN  - 0 (Gentamicins)
RN  - MC6XB22UGQ (etimicin sulfate)
SB  - IM
MH  - Acute Disease
MH  - Anti-Bacterial Agents/*administration & dosage
MH  - Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
MH  - Antitubercular Agents/*therapeutic use
MH  - Diagnosis, Differential
MH  - Gentamicins/*administration & dosage
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neck
MH  - Tuberculosis, Lymph Node/*diagnosis/*drug therapy
PMC - PMC3351659
COIS- Competing interests None.
EDAT- 2012/05/19 06:00
MHDA- 2013/02/13 06:00
PMCR- 2014/05/08
CRDT- 2012/05/19 06:00
PHST- 2012/05/19 06:00 [entrez]
PHST- 2012/05/19 06:00 [pubmed]
PHST- 2013/02/13 06:00 [medline]
PHST- 2014/05/08 00:00 [pmc-release]
AID - bcr.12.2011.5458 [pii]
AID - 10.1136/bcr.12.2011.5458 [doi]
PST - epublish
SO  - BMJ Case Rep. 2012 May 8;2012:bcr1220115458. doi: 10.1136/bcr.12.2011.5458.