PMID- 22609079 OWN - NLM STAT- MEDLINE DCOM- 20121029 LR - 20220321 IS - 1879-1883 (Electronic) IS - 0002-9610 (Linking) VI - 204 IP - 3 DP - 2012 Sep TI - Ligation of intersphincteric fistula tract compared with advancement flap for complex anorectal fistulas requiring initial seton drainage. PG - 283-9 LID - 10.1016/j.amjsurg.2011.10.025 [doi] AB - BACKGROUND: The ligation of intersphincteric fistula tract (LIFT) is a relatively new surgical technique for treating complex anorectal fistulas. METHODS: LIFT was compared with anorectal advancement flap management (ARAF) of complex anorectal fistulas requiring previous seton drainage. Crohn's patients were excluded. Patients with no confirmed recurrent sepsis after 6 months were randomized to day surgery performance of LIFT (25; 17 male) or ARAF (14; 10 male) with removal of the seton. Outcome measures included recurrences, surgical time, complications, hospital readmissions, and fecal incontinence. RESULTS: LIFT was 32.5 minutes shorter than ARAF (P < .001). Complications were similar, with no hospital readmissions. Return to normal activities was 1 week for LIFT patients, 2 weeks for ARAF patients (P = .016). At 19 months there were 3 recurrences (2 in the LIFT group). One ARAF patient had minor incontinence. CONCLUSIONS: The LIFT procedure was simple, safe, shorter, and patients returned to work earlier. All patients had preliminary seton drainage, possibly contributing to the low recurrence rates. CI - Copyright (c) 2012 Elsevier Inc. All rights reserved. FAU - Mushaya, Chrispen AU - Mushaya C AD - Department of Surgery School of Medicine, Townsville and the Australian Institute of Tropical Medicine, North Queensland Centre for Cancer Research, James Cook University, Townsville, Queensland, Australia. FAU - Bartlett, Lynne AU - Bartlett L FAU - Schulze, Bettina AU - Schulze B FAU - Ho, Yik-Hong AU - Ho YH LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial DEP - 20120519 PL - United States TA - Am J Surg JT - American journal of surgery JID - 0370473 SB - IM MH - Adult MH - Aged MH - Digestive System Surgical Procedures/adverse effects/*methods MH - *Drainage/methods MH - Fecal Incontinence/etiology MH - Female MH - Follow-Up Studies MH - Humans MH - Ligation MH - Male MH - Middle Aged MH - Pain, Postoperative/etiology MH - Patient Readmission/statistics & numerical data MH - Postoperative Care/methods MH - Rectal Fistula/pathology/*surgery MH - Recurrence MH - *Surgical Flaps MH - Surgical Wound Dehiscence/etiology MH - Treatment Outcome MH - Wound Healing EDAT- 2012/05/23 06:00 MHDA- 2012/10/30 06:00 CRDT- 2012/05/22 06:00 PHST- 2011/08/27 00:00 [received] PHST- 2011/10/27 00:00 [revised] PHST- 2011/10/27 00:00 [accepted] PHST- 2012/05/22 06:00 [entrez] PHST- 2012/05/23 06:00 [pubmed] PHST- 2012/10/30 06:00 [medline] AID - S0002-9610(12)00218-8 [pii] AID - 10.1016/j.amjsurg.2011.10.025 [doi] PST - ppublish SO - Am J Surg. 2012 Sep;204(3):283-9. doi: 10.1016/j.amjsurg.2011.10.025. Epub 2012 May 19.