PMID- 22609604
OWN - NLM
STAT- MEDLINE
DCOM- 20121002
LR  - 20131121
IS  - 1873-4367 (Electronic)
IS  - 0927-7765 (Linking)
VI  - 97
DP  - 2012 Sep 1
TI  - Smart copper oxide nanocrystals: synthesis, characterization, electrochemical and 
      potent antibacterial activity.
PG  - 201-6
LID - 10.1016/j.colsurfb.2012.04.032 [doi]
AB  - We report herein the synthesis and characterization of novel CuO nanocrystals and 
      their electrochemical and potent antibacterial activity. The utilized CuO 
      nanocrystals were prepared by wet chemical method using copper acetate and 
      hexamethylenetetramine (HMTA) as precursors. The physicochemical properties of 
      the synthesized CuO nanocrystals having size ~6 nm were determined by X-ray 
      diffractometer (XRD), energy dispersive X-ray analysis (EDX), transmission 
      electron microscopy (TEM) and ultra violet-visible (UV-Vis) spectroscopy. The 
      antibacterial study was carried out by minimum inhibitory concentration (MIC) 
      using E. coli as model organism. The MIC of the CuO nanocrystals was found to be 
      2.5 mug/ml and the TEM analysis reveals that CuO nanocrystals caused disturbance 
      to the cell wall which led to the irreversible damage to the cell envelope 
      eventually leading to cell death. Furthermore, mechanism of bactericidal action 
      of novel CuO nanocrystals is discussed in the light of our findings. 
      Additionally, the synthesized CuO nanocrystals were applied as electrode material 
      for supercapacitor. The specific capacitance of CuO nanocrystals measured at a 
      potential scan rate of 5 mV/s was as high as 164.9 F g(-1).
CI  - Copyright (c) 2012 Elsevier B.V. All rights reserved.
FAU - Hassan, M Shamshi
AU  - Hassan MS
AD  - Department of Organic Materials and Fiber Engineering, Chonbuk National 
      University, Jeonju 561-756, Republic of Korea.
FAU - Amna, Touseef
AU  - Amna T
FAU - Yang, O-Bong
AU  - Yang OB
FAU - El-Newehy, Mohamed H
AU  - El-Newehy MH
FAU - Al-Deyab, Salem S
AU  - Al-Deyab SS
FAU - Khil, Myung-Seob
AU  - Khil MS
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120428
PL  - Netherlands
TA  - Colloids Surf B Biointerfaces
JT  - Colloids and surfaces. B, Biointerfaces
JID - 9315133
RN  - 0 (Anti-Bacterial Agents)
RN  - 789U1901C5 (Copper)
RN  - T8BEA5064F (cuprous oxide)
SB  - IM
MH  - Anti-Bacterial Agents/*chemistry/*pharmacology
MH  - Copper/*chemistry/*pharmacology
MH  - Electrochemistry
MH  - Microscopy, Electron, Transmission
MH  - Nanoparticles/*chemistry/ultrastructure
MH  - Nanotechnology
MH  - X-Ray Diffraction
EDAT- 2012/05/23 06:00
MHDA- 2012/10/04 06:00
CRDT- 2012/05/22 06:00
PHST- 2012/03/19 00:00 [received]
PHST- 2012/04/17 00:00 [revised]
PHST- 2012/04/21 00:00 [accepted]
PHST- 2012/05/22 06:00 [entrez]
PHST- 2012/05/23 06:00 [pubmed]
PHST- 2012/10/04 06:00 [medline]
AID - S0927-7765(12)00251-2 [pii]
AID - 10.1016/j.colsurfb.2012.04.032 [doi]
PST - ppublish
SO  - Colloids Surf B Biointerfaces. 2012 Sep 1;97:201-6. doi: 
      10.1016/j.colsurfb.2012.04.032. Epub 2012 Apr 28.