PMID- 22611747 OWN - NLM STAT- MEDLINE DCOM- 20120628 LR - 20131121 IS - 0011-4162 (Print) IS - 0011-4162 (Linking) VI - 89 IP - 4 DP - 2012 Apr TI - Subacute cutaneous lupus erythematosus: a case report of Polypodium leucotomos as an adjuvant therapy. PG - 183-4 AB - Subacute cutaneous lupus erythematosus (SCLE) is an uncommon autoimmune disease that results in substantial photosensitivity of affected patients. Eruptions often are triggered or exacerbated by UV light (UVL) exposure. We present a case of a patient with SCLE who was moderately controlled with hydroxychloroquine sulfate but achieved near total remission of disease after the addition of oral Polypodium leucotomos supplement which has photoprotective effects on human keratinocytes. We report sustained clinical response with the use of P leucotomos in lupus and suggest that it may have future application in photosensitizing dermatoses. FAU - Breithaupt, Andrew D AU - Breithaupt AD AD - Department of Dermatology and Cutaneous Surgery, University of California, San Diego, Rady Children's Hospital, 92123, USA. FAU - Jacob, Sharon E AU - Jacob SE LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Cutis JT - Cutis JID - 0006440 RN - 0 (Antioxidants) RN - 0 (Plant Extracts) RN - 4QWG6N8QKH (Hydroxychloroquine) SB - IM MH - Administration, Oral MH - Antioxidants/*administration & dosage MH - Chemotherapy, Adjuvant MH - Humans MH - Hydroxychloroquine/*administration & dosage MH - Lupus Erythematosus, Cutaneous/*diagnosis/*drug therapy MH - Male MH - Middle Aged MH - Plant Extracts/*administration & dosage MH - *Polypodium MH - Treatment Outcome EDAT- 2012/05/23 06:00 MHDA- 2012/06/29 06:00 CRDT- 2012/05/23 06:00 PHST- 2012/05/23 06:00 [entrez] PHST- 2012/05/23 06:00 [pubmed] PHST- 2012/06/29 06:00 [medline] PST - ppublish SO - Cutis. 2012 Apr;89(4):183-4.