PMID- 22613521
OWN - NLM
STAT- MEDLINE
DCOM- 20120926
LR  - 20120522
IS  - 2542-5641 (Electronic)
IS  - 0366-6999 (Linking)
VI  - 125
IP  - 6
DP  - 2012 Mar
TI  - Coronary stenting versus bypass surgery in heart failure patients with preserved 
      ejection fraction.
PG  - 1000-4
AB  - BACKGROUND: The optimal revascularization strategy in patients with heart failure 
      with preserved ejection fraction (HFPEF) remains unclear. The aim of the present 
      study was to compare the effects of percutaneous coronary intervention (PCI) and 
      coronary artery bypass grafting (CABG) in patients with HFPEF. METHODS: From July 
      2003 through September 2005, a total of 920 patients with coronary artery disease 
      (CAD) and HFPEF (ejection fraction >/= 50%) underwent PCI (n = 350) or CABG (n = 
      570). We compared the groups with respect to the primary outcome of mortality, 
      and the secondary outcomes of main adverse cardiac and cerebral vascular events 
      (MACCE), including death, myocardial infarction, stroke and repeat 
      revascularization, at a median follow-up of 543 days. RESULTS: In-hospital 
      mortality was significantly lower in the PCI group than in the CABG group (0.3% 
      vs. 2.5%, adjusted P = 0.016). During follow-up, there was no significant 
      difference in the two groups with regard to mortality rates (2.3% vs. 3.5%, 
      adjusted P = 0.423). Patients receiving PCI had higher MACCE rates as compared 
      with patients receiving CABG (13.4% vs. 4.0%, adjusted P < 0.001), mainly due to 
      higher rate of repeat revascularization (adjusted P < 0.001). Independent 
      predictors of mortality were age, New York Heart Association (NYHA) class and 
      chronic total occlusion. CONCLUSION: Among patients with CAD and HFPEF, PCI was 
      shown to be as good as CABG with respect to the mortality rate, although there 
      was a higher rate of repeat revascularization in patients undergoing PCI.
FAU - Xue, Zeng-ming
AU  - Xue ZM
AD  - Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, 
      Beijing 100029, China.
FAU - Li, Wei-ju
AU  - Li WJ
FAU - Ma, Chang-sheng
AU  - Ma CS
FAU - Nie, Shao-ping
AU  - Nie SP
FAU - Dong, Jian-zeng
AU  - Dong JZ
FAU - Liu, Xiao-hui
AU  - Liu XH
FAU - Kang, Jun-ping
AU  - Kang JP
FAU - Lu, Qiang
AU  - Lu Q
FAU - DU, Xin
AU  - DU X
FAU - Wang, Xiao
AU  - Wang X
FAU - Chen, Fang
AU  - Chen F
FAU - Zhou, Yu-jie
AU  - Zhou YJ
FAU - Lu, Shu-zheng
AU  - Lu SZ
FAU - Huang, Fang-jiong
AU  - Huang FJ
FAU - Gu, Cheng-xiong
AU  - Gu CX
FAU - Wu, Xue-si
AU  - Wu XS
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - China
TA  - Chin Med J (Engl)
JT  - Chinese medical journal
JID - 7513795
SB  - IM
MH  - Aged
MH  - *Angioplasty, Balloon, Coronary/mortality
MH  - *Coronary Artery Bypass/mortality
MH  - Female
MH  - Heart Failure/physiopathology/*therapy
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Stents
EDAT- 2012/05/23 06:00
MHDA- 2012/09/27 06:00
CRDT- 2012/05/23 06:00
PHST- 2012/05/23 06:00 [entrez]
PHST- 2012/05/23 06:00 [pubmed]
PHST- 2012/09/27 06:00 [medline]
PST - ppublish
SO  - Chin Med J (Engl). 2012 Mar;125(6):1000-4.