PMID- 22614029
OWN - NLM
STAT- MEDLINE
DCOM- 20121105
LR  - 20211021
IS  - 1439-099X (Electronic)
IS  - 0179-7158 (Linking)
VI  - 188
IP  - 9
DP  - 2012 Sep
TI  - Patient positioning variations to reduce dose to normal tissues during 3D 
      conformal radiotherapy for high-risk prostate cancer.
PG  - 816-22
AB  - BACKGROUND AND PURPOSE: The goal of this work was to assess optimal treatment 
      positioning of 3D conformal radiotherapy (3DCRT) for high-risk prostate cancer 
      patients. PATIENTS AND METHODS: Treatment plans of 25 patients in different 
      patient positions were evaluated: with knee and ankle support (KAS) in the supine 
      position and with a belly board (BB) in the prone position both with full (FB) 
      and empty bladder (EB). Planning target volumes (PTVs) for pelvis, prostate and 
      vesicles, prostate, and organs at risk (OARs) were delineated. Dose and 
      overlapping volumes were evaluated. RESULTS: Overlapping volumes were 
      significantly smaller with a FB than with an EB. No significant differences were 
      found in overlapping volumes with respect to patient fixation systems, but the 
      percentage values of dose to the OARs showed significantly better results 
      employing KAS than a BB. A FB reduced the dose volumes to the OARs. Comparison 
      with respect to circumference of abdomen (CA) showed significantly smaller 
      overlapping at large CA in most of the cases. CONCLUSION: Supine position is 
      suggested with KAS combined with a FB (especially in cases of larger CA) when 
      using 3DCRT with planning technique modification for high-risk prostate cancer 
      patients to reduce the dose of OARs, based on our results.
FAU - Czigner, K
AU  - Czigner K
AD  - Department of Radiotherapy, National Institute of Oncology, Budapest, Hungary. 
      kczigner7@yahoo.com
FAU - Agoston, P
AU  - Agoston P
FAU - Forgacs, G
AU  - Forgacs G
FAU - Kasler, M
AU  - Kasler M
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20120523
PL  - Germany
TA  - Strahlenther Onkol
JT  - Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et 
      al]
JID - 8603469
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Positioning/*methods
MH  - Prostatic Neoplasms/*radiotherapy
MH  - Radiation Injuries/prevention & control
MH  - Radiation Protection/*methods
MH  - *Radiotherapy Dosage
MH  - Radiotherapy Planning, Computer-Assisted/*methods
MH  - Radiotherapy, Conformal/adverse effects/*methods
MH  - Treatment Outcome
EDAT- 2012/05/23 06:00
MHDA- 2012/11/06 06:00
CRDT- 2012/05/23 06:00
PHST- 2011/12/12 00:00 [received]
PHST- 2012/03/27 00:00 [accepted]
PHST- 2012/05/23 06:00 [entrez]
PHST- 2012/05/23 06:00 [pubmed]
PHST- 2012/11/06 06:00 [medline]
AID - 10.1007/s00066-012-0126-z [doi]
PST - ppublish
SO  - Strahlenther Onkol. 2012 Sep;188(9):816-22. doi: 10.1007/s00066-012-0126-z. Epub 
      2012 May 23.