PMID- 22618206
OWN - NLM
STAT- MEDLINE
DCOM- 20130620
LR  - 20211021
IS  - 1433-3023 (Electronic)
IS  - 0937-3462 (Linking)
VI  - 24
IP  - 1
DP  - 2013 Jan
TI  - Low back pain does not improve with surgical treatment of pelvic organ prolapse.
PG  - 147-53
LID - 10.1007/s00192-012-1797-9 [doi]
AB  - INTRODUCTION AND HYPOTHESIS: Our goal was to determine if there is a correlation 
      between low back pain (LBP) and pelvic organ prolapse (POP) by assessing for 
      change in LBP after surgical correction of prolapse. METHODS: Patients undergoing 
      POP surgery were recruited to participate. They completed the Oswestry Disability 
      Index (ODI), a validated back pain questionnaire, at their preoperative and 
      postoperative visits at 1, 3, and 6 months. A higher ODI score (0-100) represents 
      more severe disability. A 9-point change represents a minimal clinically 
      important difference (MCID). The primary outcome was the change in ODI scores 
      from preoperative to 3 months postoperative. We analyzed ODI scores with repeated 
      measures analysis of variance (ANOVA). Power analysis showed that a sample size 
      of 50 was needed for 88 % power to resolve a MCID on ODI. RESULTS: A total of 51 
      patients were recruited and 43 (84 %), 34 (67 %), and 36 (71 %) completed the 1-, 
      3-, and 6-month follow-up, respectively. The mean ODI scores at the preoperative 
      and the 1-, 3-, and 6-month postoperative visits were 15, 19, 9, and 9. The mean 
      ODI score from preoperative to 3 months postoperative improved by 5 points 
      [confidence interval (CI) -9.2 to -0.5, p = 0.03]. Of the participants 7 (20.6 %, 
      CI 11-35 %) experienced a MCID improvement, 24 (70.6 %, CI 56-83 %) reported no 
      substantial change, and 3 (8.8 %, CI 3-20 %) experienced a MCID worsening. 
      CONCLUSIONS: Our study found a statistically significant but not clinically 
      significant improvement of LBP after surgical repair of prolapse.
FAU - Lau, Trevin
AU  - Lau T
AD  - Massachusetts General Hospital, Boston, MA 02114, USA. tlau1@partners.org
FAU - Weinstein, Milena
AU  - Weinstein M
FAU - Wakamatsu, May
AU  - Wakamatsu M
FAU - Macklin, Eric A
AU  - Macklin EA
FAU - Pulliam, Samantha
AU  - Pulliam S
LA  - eng
PT  - Journal Article
DEP - 20120523
PL  - England
TA  - Int Urogynecol J
JT  - International urogynecology journal
JID - 101567041
SB  - IM
MH  - Adult
MH  - Aged
MH  - Analysis of Variance
MH  - Disability Evaluation
MH  - Female
MH  - Humans
MH  - Low Back Pain/*etiology/*surgery
MH  - Middle Aged
MH  - Pain Measurement
MH  - Pelvic Organ Prolapse/*complications/*surgery
MH  - Prospective Studies
MH  - Treatment Outcome
EDAT- 2012/05/24 06:00
MHDA- 2013/06/21 06:00
CRDT- 2012/05/24 06:00
PHST- 2011/12/05 00:00 [received]
PHST- 2012/04/11 00:00 [accepted]
PHST- 2012/05/24 06:00 [entrez]
PHST- 2012/05/24 06:00 [pubmed]
PHST- 2013/06/21 06:00 [medline]
AID - 10.1007/s00192-012-1797-9 [doi]
PST - ppublish
SO  - Int Urogynecol J. 2013 Jan;24(1):147-53. doi: 10.1007/s00192-012-1797-9. Epub 
      2012 May 23.