PMID- 2262228
OWN - NLM
STAT- MEDLINE
DCOM- 19910207
LR  - 20131121
IS  - 0172-4622 (Print)
IS  - 0172-4622 (Linking)
VI  - 11
IP  - 5
DP  - 1990 Oct
TI  - Changes in selected blood measures during repeated days of intense training and 
      carbohydrate control.
PG  - 362-6
AB  - Ten runners were studied to determine whether selected blood measures were useful 
      indices of the metabolic stress associated with intense training and dietary 
      carbohydrate (CHO) deficiency. The runners performed two diet/training regimens, 
      involving 5 repeated days of intense training approximately 80 min/d, 
      approximately 80% VO2max) and dietary CHO control (8.0 g.kg-1.d-1, EQ-CHO; 3.9 
      g.kg-1.d-1, LO-CHO). Resting blood samples were obtained after a 3-day control 
      period, after 3 and 5 days of intense training, and after 3 days of rest. Resting 
      uric acid levels were significantly higher (P less than 0.05) after 3 and 5 days 
      of training during the LO-CHO vs EQ-CHO regimen (353 +/- 21 vs 309 +/- 24, and 
      345 +/- 26 vs 302 +/- 26 mol.l-1, respectively). Resting thyroxine (T4) levels 
      were higher (P less than 0.05) after 5 days of training during the LO-CHO vs 
      EQ-CHO regimen (102.2 +/- 6.2 vs 83.7 +/- 4.5 nmol.l-1, respectively). While 
      creatine kinase levels were elevated after both regimens (P less than 0.05), 
      there was no difference between regimens. Serum cortisol (C) levels were reduced 
      by 10% for both regimens (P less than 0.05), possibly due to an expansion in 
      plasma volume (7.6 and 7.3% for the LO-CHO and EQ-CHO regimens, respectively). 
      Resting FFA levels were increased (P less than 0.05) during both regimens, but 
      there was no difference between the regimens.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Kirwan, J P
AU  - Kirwan JP
AD  - Human Performance Laboratory, Ball State University, Muncie, IN 47303.
FAU - Costill, D L
AU  - Costill DL
FAU - Houmard, J A
AU  - Houmard JA
FAU - Mitchell, J B
AU  - Mitchell JB
FAU - Flynn, M G
AU  - Flynn MG
FAU - Fink, W J
AU  - Fink WJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Int J Sports Med
JT  - International journal of sports medicine
JID - 8008349
RN  - 0 (Dietary Carbohydrates)
RN  - 268B43MJ25 (Uric Acid)
RN  - 9005-79-2 (Glycogen)
RN  - EC 2.7.3.2 (Creatine Kinase)
SB  - IM
MH  - Adult
MH  - Analysis of Variance
MH  - Creatine Kinase/blood
MH  - Dietary Carbohydrates/*administration & dosage/metabolism
MH  - Energy Metabolism
MH  - Glycogen/metabolism
MH  - Humans
MH  - Male
MH  - Muscles/metabolism
MH  - *Physical Education and Training
MH  - Physical Exertion/*physiology
MH  - Running
MH  - Time Factors
MH  - Uric Acid/blood
OID - NASA: 91085972
EDAT- 1990/10/01 00:00
MHDA- 1990/10/01 00:01
CRDT- 1990/10/01 00:00
PHST- 1990/10/01 00:00 [pubmed]
PHST- 1990/10/01 00:01 [medline]
PHST- 1990/10/01 00:00 [entrez]
AID - 10.1055/s-2007-1024819 [doi]
PST - ppublish
SO  - Int J Sports Med. 1990 Oct;11(5):362-6. doi: 10.1055/s-2007-1024819.