PMID- 22627787
OWN - NLM
STAT- MEDLINE
DCOM- 20140630
LR  - 20211021
IS  - 1573-2584 (Electronic)
IS  - 0301-1623 (Linking)
VI  - 45
IP  - 5
DP  - 2013 Oct
TI  - Paradoxical cryptococcal immune reconstitution inflammatory syndrome in advanced 
      chronic kidney disease.
PG  - 1505-9
LID - 10.1007/s11255-012-0196-y [doi]
AB  - Cryptococcal-related immune reconstitution inflammatory syndrome (IRIS) is 
      frequently seen in immunocompromised patients. A 45-year-old man with advanced 
      chronic kidney disease (CKD) received intensive antifungal treatment for 
      pulmonary cryptococcosis. Despite negative pleural effusion cultures and 
      declining serum cryptococcal antigen titers, the patient presented with 
      progressive pulmonary infiltration, intermittent fever, and elevated C-reactive 
      protein. Steroids were given for suspected IRIS, and the clinical condition 
      improved dramatically. This is the first report on paradoxical cryptococcal IRIS 
      in a patient with advanced CKD.
FAU - Kao, Chih-Chin
AU  - Kao CC
AD  - Division of Nephrology, National Taiwan University Hospital, College of Medicine, 
      National Taiwan University, Taipei, Taiwan.
FAU - Wu, Vin-Cent
AU  - Wu VC
FAU - Sun, Hsin-Yun
AU  - Sun HY
FAU - Wu, Che-Hsiung
AU  - Wu CH
CN  - NSARF Group
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20120525
PL  - Netherlands
TA  - Int Urol Nephrol
JT  - International urology and nephrology
JID - 0262521
RN  - 0 (Anti-Inflammatory Agents)
RN  - 0 (Antifungal Agents)
RN  - X4W7ZR7023 (Methylprednisolone)
SB  - IM
MH  - Anti-Inflammatory Agents/therapeutic use
MH  - Antifungal Agents/therapeutic use
MH  - Cryptococcosis/*complications/drug therapy/microbiology
MH  - Cryptococcus neoformans
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/*complications/drug therapy
MH  - Lung Diseases/*complications/drug therapy/microbiology
MH  - Male
MH  - Methylprednisolone/therapeutic use
MH  - Middle Aged
MH  - Renal Insufficiency, Chronic/*complications
EDAT- 2012/05/26 06:00
MHDA- 2014/07/01 06:00
CRDT- 2012/05/26 06:00
PHST- 2011/11/19 00:00 [received]
PHST- 2012/05/09 00:00 [accepted]
PHST- 2012/05/26 06:00 [entrez]
PHST- 2012/05/26 06:00 [pubmed]
PHST- 2014/07/01 06:00 [medline]
AID - 10.1007/s11255-012-0196-y [doi]
PST - ppublish
SO  - Int Urol Nephrol. 2013 Oct;45(5):1505-9. doi: 10.1007/s11255-012-0196-y. Epub 
      2012 May 25.